Russian Chemical Bulletin, volume 68, issue 11, pages 1991-1996
Structure and dynamics of photoactivatable adenylyl cyclase
Publication type: Journal Article
Publication date: 2019-11-01
Journal:
Russian Chemical Bulletin
Quartile SCImago
Q3
Quartile WOS
Q3
Impact factor: 1.7
ISSN: 10665285, 15739171
General Chemistry
Abstract
The full-atom 3D model of the dimer of the photoregulated adenylyl cyclase is constructed. It contains a molecule of flavin mononucleotide chromophore in the photoreceptor domain and a molecule of adenosine triphosphate substrate in the catalytic domain of each monomer. The performed molecular dynamics simulations show that monomers in the dimer are not equivalent, as well as that the conformation of the dimer changes upon substrate binding to the active site and also after transition of the photoreceptor domain from the dark to the light form.
Citations by journals
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Biophysics (Russian Federation)
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Biophysics (Russian Federation)
1 publication, 100%
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1
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Citations by publishers
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1
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Pleiades Publishing
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Pleiades Publishing
1 publication, 100%
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1
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GOST
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Kulakova A. M. et al. Structure and dynamics of photoactivatable adenylyl cyclase // Russian Chemical Bulletin. 2019. Vol. 68. No. 11. pp. 1991-1996.
GOST all authors (up to 50)
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Kulakova A. M., Khrenova M. G., Nemukhin A. V. Structure and dynamics of photoactivatable adenylyl cyclase // Russian Chemical Bulletin. 2019. Vol. 68. No. 11. pp. 1991-1996.
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RIS
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TY - JOUR
DO - 10.1007/s11172-019-2657-2
UR - https://doi.org/10.1007%2Fs11172-019-2657-2
TI - Structure and dynamics of photoactivatable adenylyl cyclase
T2 - Russian Chemical Bulletin
AU - Kulakova, A M
AU - Khrenova, M. G.
AU - Nemukhin, A. V.
PY - 2019
DA - 2019/11/01 00:00:00
PB - Springer Nature
SP - 1991-1996
IS - 11
VL - 68
SN - 1066-5285
SN - 1573-9171
ER -
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BibTex
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@article{2019_Kulakova,
author = {A M Kulakova and M. G. Khrenova and A. V. Nemukhin},
title = {Structure and dynamics of photoactivatable adenylyl cyclase},
journal = {Russian Chemical Bulletin},
year = {2019},
volume = {68},
publisher = {Springer Nature},
month = {nov},
url = {https://doi.org/10.1007%2Fs11172-019-2657-2},
number = {11},
pages = {1991--1996},
doi = {10.1007/s11172-019-2657-2}
}
Cite this
MLA
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Kulakova, A. M., et al. “Structure and dynamics of photoactivatable adenylyl cyclase.” Russian Chemical Bulletin, vol. 68, no. 11, Nov. 2019, pp. 1991-1996. https://doi.org/10.1007%2Fs11172-019-2657-2.