Open Access
The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells
Sabrina Bimonte
1
,
Antonio Barbieri
2
,
Maddalena Leongito
1
,
Giuseppe Palma
2
,
Vitale Del Vecchio
2
,
Michela Falco
2
,
Raffaele Palaia
1
,
Vittorio Albino
1
,
Mauro Piccirillo
1
,
Alfonso Amore
1
,
Antonella Petrillo
3
,
Vincenza Granata
3
,
Francesco Izzo
1
1
2
Publication type: Journal Article
Publication date: 2016-11-10
scimago Q2
wos Q3
SJR: 0.990
CiteScore: 9.0
Impact factor: 3.3
ISSN: 16879678, 1687966X
PubMed ID:
27006664
Molecular Biology
Cell Biology
Abstract
Pancreatic ductal adenocarcinoma is currently one of the deadliest cancers with low overall survival rate. This disease leads to an aggressive local invasion and early metastases and is poorly responsive to treatment with chemotherapy or chemoradiotherapy. Several studies have shown that pancreatic cancer stem cells (PCSCs) play different roles in the regulation of drug resistance and recurrence in pancreatic cancer. MicroRNA (miRNA), a class of newly emerging small noncoding RNAs, is involved in the modulation of several biological activities ranging from invasion to metastases development, as well as drug resistance of pancreatic cancer. In this review, we synthesize the latest findings on the role of miRNAs in regulating different biological properties of pancreatic cancer stem cells.
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15
Total citations:
15
Citations from 2024:
5
(33.33%)
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RIS |
BibTex
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GOST
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Bimonte S. et al. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells // Stem Cells International. 2016. Vol. 2016. pp. 1-7.
GOST all authors (up to 50)
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Bimonte S., Barbieri A., Leongito M., Palma G., Del Vecchio V., Falco M., Palaia R., Albino V., Piccirillo M., Amore A., Petrillo A., Granata V., Izzo F. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells // Stem Cells International. 2016. Vol. 2016. pp. 1-7.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1155/2016/8352684
UR - https://doi.org/10.1155/2016/8352684
TI - The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells
T2 - Stem Cells International
AU - Bimonte, Sabrina
AU - Barbieri, Antonio
AU - Leongito, Maddalena
AU - Palma, Giuseppe
AU - Del Vecchio, Vitale
AU - Falco, Michela
AU - Palaia, Raffaele
AU - Albino, Vittorio
AU - Piccirillo, Mauro
AU - Amore, Alfonso
AU - Petrillo, Antonella
AU - Granata, Vincenza
AU - Izzo, Francesco
PY - 2016
DA - 2016/11/10
PB - Hindawi Limited
SP - 1-7
VL - 2016
PMID - 27006664
SN - 1687-9678
SN - 1687-966X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Bimonte,
author = {Sabrina Bimonte and Antonio Barbieri and Maddalena Leongito and Giuseppe Palma and Vitale Del Vecchio and Michela Falco and Raffaele Palaia and Vittorio Albino and Mauro Piccirillo and Alfonso Amore and Antonella Petrillo and Vincenza Granata and Francesco Izzo},
title = {The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells},
journal = {Stem Cells International},
year = {2016},
volume = {2016},
publisher = {Hindawi Limited},
month = {nov},
url = {https://doi.org/10.1155/2016/8352684},
pages = {1--7},
doi = {10.1155/2016/8352684}
}