Open Access
,
volume 11
Beyond Conventional: The New Horizon of Targeted Therapy for the Treatment of Advanced Non Small Cell Lung Cancer
Alfredo Tartarone
1
,
Vittoria Lapadula
1
,
Concetta Di Micco
2
,
Gemma Rossi
3
,
Carlotta Ottanelli
3
,
Andrea Marini
3
,
Roberta Giorgione
3
,
Katia Ferrari
4
,
Martina Catalano
3
,
Luca Voltolini
5
,
Enrico Mini
6
,
Giandomenico Roviello
6
2
Publication type: Journal Article
Publication date: 2021-05-21
scimago Q2
wos Q2
SJR: 1.075
CiteScore: 6.9
Impact factor: 3.3
ISSN: 2234943X
PubMed ID:
34094913
Cancer Research
Oncology
Abstract
In the last few years the advent of targeted therapies against oncogenic drivers significantly improved the survival of non small cell lung cancer (NSCLC) patients with a favourable toxicity profile. Therefore, genetic testing, including at least EGFR mutations and ALK/ROS1 rearrangements, should be performed in all NSCLC patients (in particular with adenocarcinoma) who received a diagnosis of advanced disease. This review focuses on novel druggable oncogenic drivers, such as MET exon 14 mutations/MET amplification, RET fusions, BRAF V600E mutations, KRAS G12C mutations, NTRK rearrangements, and HER2 alterations.
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Metrics
11
Total citations:
11
Citations from 2024:
2
(18.18%)
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RIS |
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GOST
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Tartarone A. et al. Beyond Conventional: The New Horizon of Targeted Therapy for the Treatment of Advanced Non Small Cell Lung Cancer // Frontiers in Oncology. 2021. Vol. 11.
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Tartarone A., Lapadula V., Di Micco C., Rossi G., Ottanelli C., Marini A., Giorgione R., Ferrari K., Catalano M., Voltolini L., Mini E., Roviello G. Beyond Conventional: The New Horizon of Targeted Therapy for the Treatment of Advanced Non Small Cell Lung Cancer // Frontiers in Oncology. 2021. Vol. 11.
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RIS
Copy
TY - JOUR
DO - 10.3389/fonc.2021.632256
UR - https://doi.org/10.3389/fonc.2021.632256
TI - Beyond Conventional: The New Horizon of Targeted Therapy for the Treatment of Advanced Non Small Cell Lung Cancer
T2 - Frontiers in Oncology
AU - Tartarone, Alfredo
AU - Lapadula, Vittoria
AU - Di Micco, Concetta
AU - Rossi, Gemma
AU - Ottanelli, Carlotta
AU - Marini, Andrea
AU - Giorgione, Roberta
AU - Ferrari, Katia
AU - Catalano, Martina
AU - Voltolini, Luca
AU - Mini, Enrico
AU - Roviello, Giandomenico
PY - 2021
DA - 2021/05/21
PB - Frontiers Media S.A.
VL - 11
PMID - 34094913
SN - 2234-943X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Tartarone,
author = {Alfredo Tartarone and Vittoria Lapadula and Concetta Di Micco and Gemma Rossi and Carlotta Ottanelli and Andrea Marini and Roberta Giorgione and Katia Ferrari and Martina Catalano and Luca Voltolini and Enrico Mini and Giandomenico Roviello},
title = {Beyond Conventional: The New Horizon of Targeted Therapy for the Treatment of Advanced Non Small Cell Lung Cancer},
journal = {Frontiers in Oncology},
year = {2021},
volume = {11},
publisher = {Frontiers Media S.A.},
month = {may},
url = {https://doi.org/10.3389/fonc.2021.632256},
doi = {10.3389/fonc.2021.632256}
}