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Cells

, том 8 , издание 1 , страницы 43

Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer

Veronica Mollica ¹

Vincenzo Di Nunno ¹

Alessia Cimadamore ²

Antonio Lopez-Beltran ³

Liang Cheng ⁴

Matteo Santoni ⁵

Marina Scarpelli ²

Rodolfo Montironi ²

Francesco Massari ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 5 аффилиаций

Division of Oncology, S. Orsola-Malpighi Hospital, 40138 Bologna, Italy |

Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, 60126 Ancona, Italy |

Department of Surgery, Cordoba University Medical School, 14071 Cordoba, Spain |

⁴

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA |

⁵

Oncology Unit, Macerata Hospital, 62012 Macerata, Italy |

Тип публикации: Journal Article

Дата публикации: 2019-01-11

MDPI

Cells

scimago Q1

wos Q2

БС1

SJR: 1.670

CiteScore: 10.5

Impact factor: 5.2

ISSN: 20734409

DOI: 10.3390/cells8010043

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PubMed ID: 30642011

General Medicine

Краткое описание

Management of metastatic or advanced prostate cancer has acquired several therapeutic approaches that have drastically changed the course of the disease. In particular due to the high sensitivity of prostate cancer cells to hormone depletion, several agents able to inhibit hormone production or binding to nuclear receptor have been evaluated and adopted in clinical practice. However, despite several hormonal treatments being available nowadays for the management of advanced or metastatic prostate cancer, the natural history of the disease leads inexorably to the development of resistance to hormone inhibition. Findings regarding the mechanisms that drive this process are of particular and increasing interest as these are potentially related to the identification of new targetable pathways and to the development of new drugs able to improve our patients’ clinical outcomes.

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Mollica V. et al. Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer // Cells. 2019. Vol. 8. No. 1. p. 43.

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Mollica V., Di Nunno V., Cimadamore A., Lopez-Beltran A., Cheng L., Santoni M., Scarpelli M., Montironi R., Massari F. Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer // Cells. 2019. Vol. 8. No. 1. p. 43.

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TY - JOUR

DO - 10.3390/cells8010043

UR - https://doi.org/10.3390/cells8010043

TI - Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer

T2 - Cells

AU - Mollica, Veronica

AU - Di Nunno, Vincenzo

AU - Cimadamore, Alessia

AU - Lopez-Beltran, Antonio

AU - Cheng, Liang

AU - Santoni, Matteo

AU - Scarpelli, Marina

AU - Montironi, Rodolfo

AU - Massari, Francesco

PY - 2019

DA - 2019/01/11

PB - MDPI

SP - 43

IS - 1

VL - 8

PMID - 30642011

SN - 2073-4409

ER -

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@article{2019_Mollica,

author = {Veronica Mollica and Vincenzo Di Nunno and Alessia Cimadamore and Antonio Lopez-Beltran and Liang Cheng and Matteo Santoni and Marina Scarpelli and Rodolfo Montironi and Francesco Massari},

title = {Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer},

journal = {Cells},

year = {2019},

volume = {8},

publisher = {MDPI},

month = {jan},

url = {https://doi.org/10.3390/cells8010043},

number = {1},

pages = {43},

doi = {10.3390/cells8010043}

}

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Mollica, Veronica, et al. “Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer.” Cells, vol. 8, no. 1, Jan. 2019, p. 43. https://doi.org/10.3390/cells8010043.

Издатель

MDPI

Журнал

Cells

scimago Q1

wos Q2

БС1

SJR

1.670

CiteScore

10.5

Impact factor

5.2

ISSN

20734409 (Print, Electronic)