Bart Reaction

Arylarsenic acids are synthesized from aromatic diazonium compounds with alkali arsenites in the presence of cupric salts, powdered silver, or copper and this reaction is referred as the Bart reaction. Furthermore, the reaction between aromatic diazonium and arsenious chloride in the presence of trace amounts of cuprous chloride is referred to as the Scheller modification. This reaction has been applied for the synthesis of aromatic arsenic acid, which has important applications in the pharmaceutical industry for isotopic labeling. This reaction can also be used to prepare arylstibonic acid.