Microwave‐ and Ultrasonic‐Assisted Coupling Reactions

Chapter 5 Microwave- and Ultrasonic-Assisted Coupling Reactions Sandeep Yadav, Sandeep Yadav University of Delhi, Atma Ram Sanatan Dharma College, Department of Chemistry, Dhaula Kuan, Delhi, 110021 India SRM Institute of Science and Technology, Department of Chemistry, Faculty of Engineering and Technology, NCR Campus, Uttar Pradesh, 201204 IndiaSearch for more papers by this authorAnirudh P.S. Raman, Anirudh P.S. Raman University of Delhi, Atma Ram Sanatan Dharma College, Department of Chemistry, Dhaula Kuan, Delhi, 110021 India SRM Institute of Science and Technology, Department of Chemistry, Faculty of Engineering and Technology, NCR Campus, Uttar Pradesh, 201204 IndiaSearch for more papers by this authorKashmiri Lal, Kashmiri Lal Guru Jambheshwar University of Science and Technology, Department of Chemistry, Hisar, Haryana, 125001 IndiaSearch for more papers by this authorPallavi Jain, Pallavi Jain SRM Institute of Science and Technology, Department of Chemistry, Faculty of Engineering and Technology, NCR Campus, Uttar Pradesh, 201204 IndiaSearch for more papers by this authorPrashant Singh, Prashant Singh University of Delhi, Atma Ram Sanatan Dharma College, Department of Chemistry, Dhaula Kuan, Delhi, 110021 IndiaSearch for more papers by this author Sandeep Yadav, Sandeep Yadav University of Delhi, Atma Ram Sanatan Dharma College, Department of Chemistry, Dhaula Kuan, Delhi, 110021 India SRM Institute of Science and Technology, Department of Chemistry, Faculty of Engineering and Technology, NCR Campus, Uttar Pradesh, 201204 IndiaSearch for more papers by this authorAnirudh P.S. Raman, Anirudh P.S. Raman University of Delhi, Atma Ram Sanatan Dharma College, Department of Chemistry, Dhaula Kuan, Delhi, 110021 India SRM Institute of Science and Technology, Department of Chemistry, Faculty of Engineering and Technology, NCR Campus, Uttar Pradesh, 201204 IndiaSearch for more papers by this authorKashmiri Lal, Kashmiri Lal Guru Jambheshwar University of Science and Technology, Department of Chemistry, Hisar, Haryana, 125001 IndiaSearch for more papers by this authorPallavi Jain, Pallavi Jain SRM Institute of Science and Technology, Department of Chemistry, Faculty of Engineering and Technology, NCR Campus, Uttar Pradesh, 201204 IndiaSearch for more papers by this authorPrashant Singh, Prashant Singh University of Delhi, Atma Ram Sanatan Dharma College, Department of Chemistry, Dhaula Kuan, Delhi, 110021 IndiaSearch for more papers by this author Book Editor(s):Dakeshwar Kumar Verma, Dakeshwar Kumar Verma Govt. Digvijay Autonomous Postgraduate College, Department of Chemistry, Rajnandgaon, 491441 Chhattisgarh, IndiaSearch for more papers by this authorChandrabhan Verma, Chandrabhan Verma Khalifa University of Science and Technology, Department of Chemical Engineering, P.O. Box, Abu Dhabi, 127788 United Arab EmiratesSearch for more papers by this authorPaz Otero Fuertes, Paz Otero Fuertes University of Vigo Faculty of Food Science and Technology, Analytical and Food Chemistry Department, Ourense, 32004 SpainSearch for more papers by this author First published: 28 March 2024 https://doi.org/10.1002/9783527844494.ch5 AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onEmailFacebookTwitterLinkedInRedditWechat Summary Microwave- and ultrasound-assisted coupling reactions have emerged as highly influential techniques in the realm of synthetic chemistry, presenting a significant breakthrough in the field of organic synthesis. These innovative methods leverage the distinctive characteristics of high-frequency microwaves and sound waves to accelerate and enhance the efficiency of various coupling processes. This chapter offers a comprehensive overview of recent research endeavors that have employed microwave and ultrasound irradiation for coupling reactions, resulting in notable improvements such as increased yields and reduced reaction times. These techniques have demonstrated exceptional advantages compared to conventional approaches, encompassing elevated reaction rates, enhanced yields, and the capacity to perform reactions under milder conditions. The chapter delves into the fundamental principles underlying microwave- and ultrasound-assisted coupling reactions, emphasizing the pivotal role of microwave heating and acoustic cavitation in stimulating bond activation and facilitating coupling processes. Furthermore, it explores the influence of solvents on these reactions and the wide-ranging applicability of microwave- and ultrasound-assisted techniques to diverse coupling reactions. Concluding the chapter, future prospects and potential advancements in the field are discussed, underscoring the promising role of microwave- and ultrasound-assisted coupling reactions in advancing the domain of synthetic chemistry. References De Souza , L.F. , Silva , L.C. , Oliveira , B.L. , and Antunes , O.A.C. ( 2008 ). Microwave- and ultrasound-assisted Suzuki – Miyaura cross-coupling reactions catalyzed by Pd/PVP . Tetrahedron Lett. 49 : 3895 – 3898 . https://doi.org/10.1016/j.tetlet.2008.04.061 . 10.1016/j.tetlet.2008.04.061 CASWeb of Science®Google Scholar Dhanush , P.C. , Veetil , P. , and Anilkumar , G. ( 2021 ). Microwave assisted C-H activation reaction: an overview . 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