Advanced Engineering Materials, volume 23, issue 5, pages 2001373

Nonwoven Scaffolds Under Tension: In Situ High‐Resolution Ultrasound Observation of Microstructure Evolution in the Volume

Publication typeJournal Article
Publication date2021-02-08
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor3.6
ISSN14381656, 15272648
Condensed Matter Physics
General Materials Science
Abstract

Fibrous scaffolds represent the basic material for tissue engineering, where creation of matrices with predictable properties is an important issue. Typically, the assessment of scaffold characteristics, including the mechanical behavior, is conducted in the air environment that is far from the natural physiological conditions in a living organism, despite possible differences in the properties obtained in dry and water‐filled specimens. The studies of the mechanical behavior of scaffolds in the wet environment are limited by the properties of visualization methods. The optimal method for studying fibrous objects in the wet environment is ultrasonic techniques, for which water immersion is a prerequisite for the experiment. Herein, a high‐frequency (200 MHz) acoustic microscopy is combined with a horizontal mechanical testing machine for in situ visualization of microstructural transformation in the volume of elastic and rigid electrospun scaffolds under tension. For the first time, the results show that in situ ultrasound monitoring provides high‐resolution imaging of the internal microstructure in water‐filled specimens. This work provides the foundation for future experimental setups for characterization of tissue‐engineered constructs in the conditions close to those in a living organism.

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Morokov E. S., Zykova A., Tyubaeva P. Nonwoven Scaffolds Under Tension: In Situ High‐Resolution Ultrasound Observation of Microstructure Evolution in the Volume // Advanced Engineering Materials. 2021. Vol. 23. No. 5. p. 2001373.
GOST all authors (up to 50) Copy
Morokov E. S., Zykova A., Tyubaeva P. Nonwoven Scaffolds Under Tension: In Situ High‐Resolution Ultrasound Observation of Microstructure Evolution in the Volume // Advanced Engineering Materials. 2021. Vol. 23. No. 5. p. 2001373.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1002/adem.202001373
UR - https://doi.org/10.1002%2Fadem.202001373
TI - Nonwoven Scaffolds Under Tension: In Situ High‐Resolution Ultrasound Observation of Microstructure Evolution in the Volume
T2 - Advanced Engineering Materials
AU - Tyubaeva, Polina
AU - Zykova, Anna
AU - Morokov, Egor S.
PY - 2021
DA - 2021/02/08 00:00:00
PB - Wiley
SP - 2001373
IS - 5
VL - 23
SN - 1438-1656
SN - 1527-2648
ER -
BibTex |
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BibTex Copy
@article{2021_Morokov,
author = {Polina Tyubaeva and Anna Zykova and Egor S. Morokov},
title = {Nonwoven Scaffolds Under Tension: In Situ High‐Resolution Ultrasound Observation of Microstructure Evolution in the Volume},
journal = {Advanced Engineering Materials},
year = {2021},
volume = {23},
publisher = {Wiley},
month = {feb},
url = {https://doi.org/10.1002%2Fadem.202001373},
number = {5},
pages = {2001373},
doi = {10.1002/adem.202001373}
}
MLA
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MLA Copy
Morokov, Egor S., et al. “Nonwoven Scaffolds Under Tension: In Situ High‐Resolution Ultrasound Observation of Microstructure Evolution in the Volume.” Advanced Engineering Materials, vol. 23, no. 5, Feb. 2021, p. 2001373. https://doi.org/10.1002%2Fadem.202001373.
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