Synthesis of Substituted Pyrimido[1,2‐ b ]indazoles through (3+2+1) Cyclization of 3‐Aminoindazoles, Ketones, and N , N ‐Dimethylaminoethanol as One‐Carbon Synthon
Publication type: Journal Article
Publication date: 2022-09-01
scimago Q1
wos Q1
SJR: 0.930
CiteScore: 8.0
Impact factor: 4.0
ISSN: 16154150, 16154169
General Chemistry
Abstract
2-Mono- or 2,3-disubstituted pyrimido[1,2-b]indazoles are synthesized by a (3+2+1) three-component cyclization of 3-aminoindazoles, ketones, and N,N-dimethylaminoethanol as a methine source. The reaction demonstrates good tolerance of both aromatic and aliphatic ketones, as well as various substitution patterns in air. A plausible mechanism is discussed.
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15
Total citations:
15
Citations from 2024:
11
(73.34%)
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Qin Z. et al. Synthesis of Substituted Pyrimido[1,2‐ b ]indazoles through (3+2+1) Cyclization of 3‐Aminoindazoles, Ketones, and N , N ‐Dimethylaminoethanol as One‐Carbon Synthon // Advanced Synthesis and Catalysis. 2022. Vol. 364. No. 18. pp. 3263-3272.
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Qin Z., Ma R., Ying S., Li F., Ma Y. Synthesis of Substituted Pyrimido[1,2‐ b ]indazoles through (3+2+1) Cyclization of 3‐Aminoindazoles, Ketones, and N , N ‐Dimethylaminoethanol as One‐Carbon Synthon // Advanced Synthesis and Catalysis. 2022. Vol. 364. No. 18. pp. 3263-3272.
Cite this
RIS
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TY - JOUR
DO - 10.1002/adsc.202200707
UR - https://doi.org/10.1002/adsc.202200707
TI - Synthesis of Substituted Pyrimido[1,2‐ b ]indazoles through (3+2+1) Cyclization of 3‐Aminoindazoles, Ketones, and N , N ‐Dimethylaminoethanol as One‐Carbon Synthon
T2 - Advanced Synthesis and Catalysis
AU - Qin, Zemin
AU - Ma, Renchao
AU - Ying, Shenpeng
AU - Li, Fanzhu
AU - Ma, Yongmin
PY - 2022
DA - 2022/09/01
PB - Wiley
SP - 3263-3272
IS - 18
VL - 364
SN - 1615-4150
SN - 1615-4169
ER -
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BibTex (up to 50 authors)
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@article{2022_Qin,
author = {Zemin Qin and Renchao Ma and Shenpeng Ying and Fanzhu Li and Yongmin Ma},
title = {Synthesis of Substituted Pyrimido[1,2‐ b ]indazoles through (3+2+1) Cyclization of 3‐Aminoindazoles, Ketones, and N , N ‐Dimethylaminoethanol as One‐Carbon Synthon},
journal = {Advanced Synthesis and Catalysis},
year = {2022},
volume = {364},
publisher = {Wiley},
month = {sep},
url = {https://doi.org/10.1002/adsc.202200707},
number = {18},
pages = {3263--3272},
doi = {10.1002/adsc.202200707}
}
Cite this
MLA
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Qin, Zemin, et al. “Synthesis of Substituted Pyrimido[1,2‐ b ]indazoles through (3+2+1) Cyclization of 3‐Aminoindazoles, Ketones, and N , N ‐Dimethylaminoethanol as One‐Carbon Synthon.” Advanced Synthesis and Catalysis, vol. 364, no. 18, Sep. 2022, pp. 3263-3272. https://doi.org/10.1002/adsc.202200707.