Open Access
Clinical Case Reports, volume 3, issue 11, pages 955-959
Spontaneous remission in three cases of AML M5 with NPM 1 mutation
Vincent Camus
1, 2
,
Pascaline Etancelin
2, 3
,
Fabrice Jardin
1, 2
,
Pascal Lenain
1
,
Nathalie Contentin
1
,
Sylvie Daliphard
4
,
Gérard Buchonnet
4
,
Emilie Lemasle
1
,
Hélène Lanic
1
,
Stéphane Lepretre
1, 2
,
Dominique Penther
3
,
Sydney Dubois
1, 2
,
Hervé Tilly
1, 2
,
Christian Bastard
2, 3
,
Aspasia Stamatoullas
1, 2
4
Department of Biological Haematology Charles Nicolle University Hospital 76000 Rouen France
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Publication type: Journal Article
Publication date: 2015-10-21
DOI:
10.1002/ccr3.408
PubMed ID:
26576281
General Medicine
Abstract
Patients with NPM1-mutated AML M5 who develop spontaneous remission (SR) after antibiotic therapy at diagnosis seem to form a favorable prognosis and chemo sensitive subtype. We report three cases of AML M5 patients with the same genotype that experienced transient SR and are now leukemia free after standard treatment.
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