ChemCatChem, volume 16, issue 7
Ruthenium‐catalyzed asymmetric ene‐yne metathesis
Meng Liu
1
,
Morwenna S M Pearson Long
1
,
Philippe Bertus
1
,
Fabien Boeda
1
1
Institut des Molécules et Matériaux du Mans, IMMM UMR 6283 CNRS - Le Mans Université Avenue Olivier Messiaen 72085 Le Mans Cedex 09 France
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Publication type: Journal Article
Publication date: 2024-01-23
Journal:
ChemCatChem
scimago Q1
SJR: 1.034
CiteScore: 8.1
Impact factor: 3.8
ISSN: 18673880, 18673899
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Abstract
The first studies on [Ru]‐catalyzed Asymmetric Ring‐Closing Ene‐Yne Metathesis (ARCEYM) are disclosed in this communication. The desymmetrization of achiral ene‐diyne substrates afforded the corresponding exo cyclic compounds in good yields and enantioselectivities (up to 69 % ee). The methodology provided a straightforward access to functionalized scaffolds displaying alkyne and diene useful for further functionalization such as [4+2] cycloaddition reaction.
Found
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