том 2008 издание 16 страницы 2817-2824

Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis

Тип публикацииJournal Article
Дата публикации2008-06-01
SCImago Q2
WOS Q2
БС2
SJR0.497
CiteScore4.3
Impact factor2.7
ISSN1434193X, 10990690
Organic Chemistry
Physical and Theoretical Chemistry
Краткое описание
The synthesis of several α-substituted N-Boc-protected prolines has been achieved by cross metathesis (CM) of N-Boc-allylproline 5 with terminal long chain alkenes and alkenes bearing hydroxy, silyloxy, ester, and O-acetylglucosamido groups. The CM occurred with good selectivity and short reaction time under microwave heating conditions, affording yields in the range of 40–92 %. Addition of Ti(OiPr)4 as a Lewis acid allowed a slight increase of the yield in the case of alkenes with Lewis basic substituents. The CM was also successfully applied to allylproline protected with trichloroacetaldehyde 4, but the intermediate products were less practical for further deprotection and elaboration. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
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ГОСТ |
Цитировать
Lumini M. et al. Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis // European Journal of Organic Chemistry. 2008. Vol. 2008. No. 16. pp. 2817-2824.
ГОСТ со всеми авторами (до 50) Скопировать
Lumini M., Cordero F. M., Pisaneschi F., Brandi A. Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis // European Journal of Organic Chemistry. 2008. Vol. 2008. No. 16. pp. 2817-2824.
RIS |
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TY - JOUR
DO - 10.1002/ejoc.200800044
UR - https://doi.org/10.1002/ejoc.200800044
TI - Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis
T2 - European Journal of Organic Chemistry
AU - Lumini, Marco
AU - Cordero, Franca M
AU - Pisaneschi, Federica
AU - Brandi, Alberto
PY - 2008
DA - 2008/06/01
PB - Wiley
SP - 2817-2824
IS - 16
VL - 2008
SN - 1434-193X
SN - 1099-0690
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2008_Lumini,
author = {Marco Lumini and Franca M Cordero and Federica Pisaneschi and Alberto Brandi},
title = {Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis},
journal = {European Journal of Organic Chemistry},
year = {2008},
volume = {2008},
publisher = {Wiley},
month = {jun},
url = {https://doi.org/10.1002/ejoc.200800044},
number = {16},
pages = {2817--2824},
doi = {10.1002/ejoc.200800044}
}
MLA
Цитировать
Lumini, Marco, et al. “Straightforward Synthesis of α-Substituted Prolines by Cross-Metathesis.” European Journal of Organic Chemistry, vol. 2008, no. 16, Jun. 2008, pp. 2817-2824. https://doi.org/10.1002/ejoc.200800044.
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