volume 26 issue 24

Kdo Glycosylations and their Application in the Oligosaccharides Synthesis

Tapan Kumar Pradhan 1
1
 
Chemistry Department Krishnath College Murshidabad West Bengal 742101 India
Publication typeJournal Article
Publication date2023-06-05
scimago Q2
wos Q2
SJR0.558
CiteScore4.3
Impact factor2.7
ISSN1434193X, 10990690
Organic Chemistry
Physical and Theoretical Chemistry
Abstract

Higher carbon saccharide 3‐deoxy‐dmanno‐oct‐2‐ulosonic acid (Kdo) is a structural unit of bacterial lipopolysaccharides (LPSs) and capsular polysaccharides (CPSs). Kdo is present in the inner core region of LPSs, and this region is structurally conserved. Being non‐mammalian in origin, Kdos are effectively recognized by the native and adaptive immune systems. Therefore, the synthesis of new Kdo derivatives and neoglycoconjugates is highly important for the development of vaccines. This review highlights recent accomplishments related to αglycosylations, β‐glycosylations and C‐glycosylations of Kdos and their application to the stereoselective synthesis of inner core oligosaccharides.

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GOST Copy
Kumar Pradhan T. Kdo Glycosylations and their Application in the Oligosaccharides Synthesis // European Journal of Organic Chemistry. 2023. Vol. 26. No. 24.
GOST all authors (up to 50) Copy
Kumar Pradhan T. Kdo Glycosylations and their Application in the Oligosaccharides Synthesis // European Journal of Organic Chemistry. 2023. Vol. 26. No. 24.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1002/ejoc.202300146
UR - https://doi.org/10.1002/ejoc.202300146
TI - Kdo Glycosylations and their Application in the Oligosaccharides Synthesis
T2 - European Journal of Organic Chemistry
AU - Kumar Pradhan, Tapan
PY - 2023
DA - 2023/06/05
PB - Wiley
IS - 24
VL - 26
SN - 1434-193X
SN - 1099-0690
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Kumar Pradhan,
author = {Tapan Kumar Pradhan},
title = {Kdo Glycosylations and their Application in the Oligosaccharides Synthesis},
journal = {European Journal of Organic Chemistry},
year = {2023},
volume = {26},
publisher = {Wiley},
month = {jun},
url = {https://doi.org/10.1002/ejoc.202300146},
number = {24},
doi = {10.1002/ejoc.202300146}
}