Electrophoresis, volume 43, issue 4, pages 535-542
Electrophoretic mobility of ester betulin derivatives and their complexation with γ‐cyclodextrin studied by capillary electrophoresis in aqueous solutions at different pH values
Publication type: Journal Article
Publication date: 2021-11-23
Journal:
Electrophoresis
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor: 2.9
ISSN: 01730835, 15222683
Biochemistry
Clinical Biochemistry
Analytical Chemistry
Abstract
In this article, capillary electrophoresis was used to measure the effective electrophoretic mobility of ester betulin derivatives as a pH function and to study their complexation with γ-cyclodextrin (γ-CD). The electrophoretic mobility of betulin 3,28-diphthalate (DPhB) and 3,28-disuccinate (DScB) changed unusually with decreasing pH: instead of decreasing, it first increased and then decreased. This fact as well as the turbidity of sample solutions at pH from 2.5 to 6, broadening of electrophoretic peaks and a decrease in the surface tension of the solutions indicates that these betulin derivatives, being amphiphilic compounds and weak acids, exist as micelles in aqueous solutions at pH 6 and below. The inclusion complexation of betulin derivatives with γ-CD at pH 9.18 and 4.5 was studied by mobility shift affinity capillary electrophoresis. At pH 9.18, the apparent binding (stability) constant logarithms for 1:1 γ-CD complexes of DPhB, betulin 3,28-disulfate (DSB) and DScB with 95% confidence interval limits were equal to 7.44 ± 0.02, 7.09 (7.01-7.19), and 6.97 (6.87-7.08) at 25°C, respectively. At pH 4.5, the binding constant for the DSB complex was slightly lower, while the micelle formation did not allow determining the exact values of the constants for the DPhB and DScB complexes.
Citations by journals
|
1
|
|
|
Journal of Inclusion Phenomena and Macrocyclic Chemistry
|
Journal of Inclusion Phenomena and Macrocyclic Chemistry
1 publication, 25%
|
|
Journal of Separation Science
|
Journal of Separation Science
1 publication, 25%
|
|
Electrophoresis
|
Electrophoresis
1 publication, 25%
|
|
Russian Journal of Physical Chemistry A
|
Russian Journal of Physical Chemistry A
1 publication, 25%
|
|
1
|
Citations by publishers
|
1
2
|
|
|
Wiley
|
Wiley
2 publications, 50%
|
|
Springer Nature
|
Springer Nature
1 publication, 25%
|
|
Pleiades Publishing
|
Pleiades Publishing
1 publication, 25%
|
|
1
2
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2022,2023],"ids":[0,0],"codes":[0,0],"imageUrls":["",""],"datasets":[{"label":"Citations number","data":[1,3],"backgroundColor":["#3B82F6","#3B82F6"],"percentage":["25","75"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Journal of Inclusion Phenomena and Macrocyclic Chemistry","Journal of Separation Science","Electrophoresis","Russian Journal of Physical Chemistry A"],"ids":[19613,17445,23809,6134],"codes":[0,0,0,0],"imageUrls":["\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp"],"datasets":[{"label":"","data":[1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[25,25,25,25],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Wiley","Springer Nature","Pleiades Publishing"],"ids":[11,8,101],"codes":[0,0,0],"imageUrls":["\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp"],"datasets":[{"label":"","data":[2,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":[50,25,25],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Sursyakova V. V. et al. Electrophoretic mobility of ester betulin derivatives and their complexation with γ‐cyclodextrin studied by capillary electrophoresis in aqueous solutions at different pH values // Electrophoresis. 2021. Vol. 43. No. 4. pp. 535-542.
GOST all authors (up to 50)
Copy
Sursyakova V. V., Levdansky V. A., Rubaylo A. I. Electrophoretic mobility of ester betulin derivatives and their complexation with γ‐cyclodextrin studied by capillary electrophoresis in aqueous solutions at different pH values // Electrophoresis. 2021. Vol. 43. No. 4. pp. 535-542.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/elps.202100173
UR - https://doi.org/10.1002%2Felps.202100173
TI - Electrophoretic mobility of ester betulin derivatives and their complexation with γ‐cyclodextrin studied by capillary electrophoresis in aqueous solutions at different pH values
T2 - Electrophoresis
AU - Levdansky, Vladimir A.
AU - Rubaylo, Anatoly I
AU - Sursyakova, Viktoria V
PY - 2021
DA - 2021/11/23 00:00:00
PB - Wiley
SP - 535-542
IS - 4
VL - 43
SN - 0173-0835
SN - 1522-2683
ER -
Cite this
BibTex
Copy
@article{2021_Sursyakova,
author = {Vladimir A. Levdansky and Anatoly I Rubaylo and Viktoria V Sursyakova},
title = {Electrophoretic mobility of ester betulin derivatives and their complexation with γ‐cyclodextrin studied by capillary electrophoresis in aqueous solutions at different pH values},
journal = {Electrophoresis},
year = {2021},
volume = {43},
publisher = {Wiley},
month = {nov},
url = {https://doi.org/10.1002%2Felps.202100173},
number = {4},
pages = {535--542},
doi = {10.1002/elps.202100173}
}
Cite this
MLA
Copy
Sursyakova, Viktoria V., et al. “Electrophoretic mobility of ester betulin derivatives and their complexation with γ‐cyclodextrin studied by capillary electrophoresis in aqueous solutions at different pH values.” Electrophoresis, vol. 43, no. 4, Nov. 2021, pp. 535-542. https://doi.org/10.1002%2Felps.202100173.