Synthesis of 1-aryl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acids and esters
1
Lilly Research Laboratories, Division of Eli Lilly & Company, Greenfield, Indiana 46140
|
Publication type: Journal Article
Publication date: 1987-05-01
scimago Q3
wos Q2
SJR: 0.362
CiteScore: 4.7
Impact factor: 2.4
ISSN: 0022152X, 19435193
Organic Chemistry
Abstract
Ethyl 1-aryl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylates 2 were prepared by the condensation of arylhydrazines with ethyl 3-ethoxy-2-(trifluoroacetyl)-2-propenoate (1a) at low temperature. The corresponding acids were also synthesized. X-ray diffraction analysis of an amide derivative 4 verified the position of the trifluoromethyl group on the pyrazole ring.
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15
Total citations:
15
Citations from 2024:
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GOST
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Beck J. R., Wright F. L. Synthesis of 1-aryl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acids and esters // Journal of Heterocyclic Chemistry. 1987. Vol. 24. No. 3. pp. 739-740.
GOST all authors (up to 50)
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Beck J. R., Wright F. L. Synthesis of 1-aryl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acids and esters // Journal of Heterocyclic Chemistry. 1987. Vol. 24. No. 3. pp. 739-740.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/jhet.5570240338
UR - https://doi.org/10.1002/jhet.5570240338
TI - Synthesis of 1-aryl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acids and esters
T2 - Journal of Heterocyclic Chemistry
AU - Beck, James R
AU - Wright, Fred L
PY - 1987
DA - 1987/05/01
PB - Wiley
SP - 739-740
IS - 3
VL - 24
SN - 0022-152X
SN - 1943-5193
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1987_Beck,
author = {James R Beck and Fred L Wright},
title = {Synthesis of 1-aryl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acids and esters},
journal = {Journal of Heterocyclic Chemistry},
year = {1987},
volume = {24},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002/jhet.5570240338},
number = {3},
pages = {739--740},
doi = {10.1002/jhet.5570240338}
}
Cite this
MLA
Copy
Beck, James R., and Fred L Wright. “Synthesis of 1-aryl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acids and esters.” Journal of Heterocyclic Chemistry, vol. 24, no. 3, May. 1987, pp. 739-740. https://doi.org/10.1002/jhet.5570240338.