Wiley
Journal of Heterocyclic Chemistry
,  том 43 ,  издание 4 ,  страницы 1099-1104

Synthetic approaches to bridgehead nitrogen methanesulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, potential cox-2 selective inhibitors

Тип публикации: Journal Article
Дата публикации: 2006-07-01
Wiley
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SJR: 0.362
CiteScore: 4.7
Impact factor: 2.4
ISSN: 0022152X, 19435193
Organic Chemistry
Краткое описание
Methane sulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyimidin-4(1H)-one, potential selective COX-2 inhibitors, were synthesized and their structural elucidation is here reported. Some derivatives, at 10 μM concentration, showed a significant percentage of inhibition in some in vitro experiments.
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Granata G. et al. Synthetic approaches to bridgehead nitrogen methanesulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, potential cox-2 selective inhibitors // Journal of Heterocyclic Chemistry. 2006. Vol. 43. No. 4. pp. 1099-1104.
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Granata G., Barbagallo S., Perdicaro A., Marrazzo A., Santagati A., Lombardo L., Cardile V. Synthetic approaches to bridgehead nitrogen methanesulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, potential cox-2 selective inhibitors // Journal of Heterocyclic Chemistry. 2006. Vol. 43. No. 4. pp. 1099-1104.
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TY - JOUR
DO - 10.1002/jhet.5570430443
UR - https://doi.org/10.1002/jhet.5570430443
TI - Synthetic approaches to bridgehead nitrogen methanesulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, potential cox-2 selective inhibitors
T2 - Journal of Heterocyclic Chemistry
AU - Granata, Giuseppe
AU - Barbagallo, Salvatore
AU - Perdicaro, Antonio
AU - Marrazzo, Agostino
AU - Santagati, Andrea
AU - Lombardo, Laura
AU - Cardile, Venera
PY - 2006
DA - 2006/07/01
PB - Wiley
SP - 1099-1104
IS - 4
VL - 43
SN - 0022-152X
SN - 1943-5193
ER -
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@article{2006_Granata,
author = {Giuseppe Granata and Salvatore Barbagallo and Antonio Perdicaro and Agostino Marrazzo and Andrea Santagati and Laura Lombardo and Venera Cardile},
title = {Synthetic approaches to bridgehead nitrogen methanesulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, potential cox-2 selective inhibitors},
journal = {Journal of Heterocyclic Chemistry},
year = {2006},
volume = {43},
publisher = {Wiley},
month = {jul},
url = {https://doi.org/10.1002/jhet.5570430443},
number = {4},
pages = {1099--1104},
doi = {10.1002/jhet.5570430443}
}
MLA
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Granata, Giuseppe, et al. “Synthetic approaches to bridgehead nitrogen methanesulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, potential cox-2 selective inhibitors.” Journal of Heterocyclic Chemistry, vol. 43, no. 4, Jul. 2006, pp. 1099-1104. https://doi.org/10.1002/jhet.5570430443.