Wiley
Journal of Labelled Compounds and Radiopharmaceuticals
,  volume 18 ,  issue 8 ,  pages 1177-1184

Synthesis of [7-3H]-3β, 16β-dihydoxy-5-androsten-17-one

Publication type: Journal Article
Publication date: 1981-08-01
Wiley
scimago Q3
wos Q4
SJR: 0.271
CiteScore: 2.0
Impact factor: 0.9
ISSN: 03624803, 10991344
Organic Chemistry
Drug Discovery
Biochemistry
Spectroscopy
Analytical Chemistry
Radiology, Nuclear Medicine and imaging
Abstract
A method has been described for the synthesis of tritiated [7-3H]-3β,16β-dihydroxy-5-androsten-17-one of high specific activity starting from [7-3H]-5-androsten-17-one. The identity of the radioactive steroid was established by thin layer chromato-graphy, gas chromatography and gas chromatography combined with mass spectroscopy. The radiolabelled steroid may be used to study its disposition and metabolism in experimental animals and also to further investigate the potential role of 3β,16β-dihydroxy-5-androsten-17-one in patients with low renin essential hypertension.
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FRANKLIN R. B., McMurtry R. J., Nelson S. D. Synthesis of [7-3H]-3β, 16β-dihydoxy-5-androsten-17-one // Journal of Labelled Compounds and Radiopharmaceuticals. 1981. Vol. 18. No. 8. pp. 1177-1184.
GOST all authors (up to 50) Copy
FRANKLIN R. B., McMurtry R. J., Nelson S. D. Synthesis of [7-3H]-3β, 16β-dihydoxy-5-androsten-17-one // Journal of Labelled Compounds and Radiopharmaceuticals. 1981. Vol. 18. No. 8. pp. 1177-1184.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1002/jlcr.2580180812
UR - https://doi.org/10.1002/jlcr.2580180812
TI - Synthesis of [7-3H]-3β, 16β-dihydoxy-5-androsten-17-one
T2 - Journal of Labelled Compounds and Radiopharmaceuticals
AU - FRANKLIN, RONALD B.
AU - McMurtry, Randolph J.
AU - Nelson, Sidney D.
PY - 1981
DA - 1981/08/01
PB - Wiley
SP - 1177-1184
IS - 8
VL - 18
SN - 0362-4803
SN - 1099-1344
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{1981_FRANKLIN,
author = {RONALD B. FRANKLIN and Randolph J. McMurtry and Sidney D. Nelson},
title = {Synthesis of [7-3H]-3β, 16β-dihydoxy-5-androsten-17-one},
journal = {Journal of Labelled Compounds and Radiopharmaceuticals},
year = {1981},
volume = {18},
publisher = {Wiley},
month = {aug},
url = {https://doi.org/10.1002/jlcr.2580180812},
number = {8},
pages = {1177--1184},
doi = {10.1002/jlcr.2580180812}
}
MLA
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MLA Copy
FRANKLIN, RONALD B., et al. “Synthesis of [7-3H]-3β, 16β-dihydoxy-5-androsten-17-one.” Journal of Labelled Compounds and Radiopharmaceuticals, vol. 18, no. 8, Aug. 1981, pp. 1177-1184. https://doi.org/10.1002/jlcr.2580180812.