Laser spectroscopic methods for the characterization of open and closed follicles
Publication type: Journal Article
Publication date: 2004-01-01
scimago Q3
wos Q3
SJR: 0.324
CiteScore: 3.0
Impact factor: 1.4
ISSN: 16122011, 1612202X
Physics and Astronomy (miscellaneous)
Instrumentation
Abstract
Hair follicles have been assigned an increasingly significant role in dermatopharmacology. Previous studies have shown that the penetration of substances into the follicle depends on its activity. Telogen follicles that were not producing sebum were closed for follicular penetration. The present study uses optical coherence tomography (OCT) to show that the orifices of inactive follicles are blocked by plugs formed of corneocytes. The follicular penetration of a fluorescent dye was analyzed by cyanoacrylate surface biopsies in combination with laser scanning microscopy. Surface exfoliation and cyanoacrylate surface peels were used as a pre-treatment to remove the corneocyte plugs from the follicular orifices and therefore to open up closed follicles. It was shown that both procedures could increase the number of open hair follicles significantly. The present experiments show that OCT in combination with laser scanning microscopy is an excellent non-invasive in vivo method for the investigation of hair follicle properties and follicular penetration processes.
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Total citations:
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Citations from 2024:
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GOST
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Otberg N. et al. Laser spectroscopic methods for the characterization of open and closed follicles // Laser Physics Letters. 2004. Vol. 1. No. 1. pp. 46-49.
GOST all authors (up to 50)
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Otberg N., Richter H., Knuttel A., H S., Sterry W., Lademann J. Laser spectroscopic methods for the characterization of open and closed follicles // Laser Physics Letters. 2004. Vol. 1. No. 1. pp. 46-49.
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RIS
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TY - JOUR
DO - 10.1002/lapl.200310011
UR - https://doi.org/10.1002/lapl.200310011
TI - Laser spectroscopic methods for the characterization of open and closed follicles
T2 - Laser Physics Letters
AU - Otberg, N.
AU - Richter, H.
AU - Knuttel, A
AU - H, Schaefer
AU - Sterry, W.
AU - Lademann, Jürgen
PY - 2004
DA - 2004/01/01
PB - IOP Publishing
SP - 46-49
IS - 1
VL - 1
SN - 1612-2011
SN - 1612-202X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2004_Otberg,
author = {N. Otberg and H. Richter and A Knuttel and Schaefer H and W. Sterry and Jürgen Lademann},
title = {Laser spectroscopic methods for the characterization of open and closed follicles},
journal = {Laser Physics Letters},
year = {2004},
volume = {1},
publisher = {IOP Publishing},
month = {jan},
url = {https://doi.org/10.1002/lapl.200310011},
number = {1},
pages = {46--49},
doi = {10.1002/lapl.200310011}
}
Cite this
MLA
Copy
Otberg, N., et al. “Laser spectroscopic methods for the characterization of open and closed follicles.” Laser Physics Letters, vol. 1, no. 1, Jan. 2004, pp. 46-49. https://doi.org/10.1002/lapl.200310011.