Wiley
Medicinal Research Reviews
,  volume 45 ,  issue 5 ,  pages 1307-1322

Recent Developments in the Optical Control of Adrenergic Signaling

Publication type: Journal Article
Publication date: 2025-04-03
Wiley
scimago Q1
wos Q1
SJR: 3.169
CiteScore: 29.5
Impact factor: 11.6
ISSN: 01986325, 10981128
Abstract
ABSTRACT

Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the optical control of AR signaling, encompassing optogenetics, photocaged compounds, and photoswitchable compounds. We also discuss the limitations of current tools and provide an outlook on the next generation of optogenetic and photopharmacological tools. These emerging optical technologies not only enhance our understanding of AR signaling but also pave the way for potential therapeutic developments.

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Shi S. et al. Recent Developments in the Optical Control of Adrenergic Signaling // Medicinal Research Reviews. 2025. Vol. 45. No. 5. pp. 1307-1322.
GOST all authors (up to 50) Copy
Shi S., Cao Y., Wijtmans M., Vischer H. F., LEURS R. Recent Developments in the Optical Control of Adrenergic Signaling // Medicinal Research Reviews. 2025. Vol. 45. No. 5. pp. 1307-1322.
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RIS Copy
TY - JOUR
DO - 10.1002/med.22110
UR - https://onlinelibrary.wiley.com/doi/10.1002/med.22110
TI - Recent Developments in the Optical Control of Adrenergic Signaling
T2 - Medicinal Research Reviews
AU - Shi, Shuang
AU - Cao, Yangzhi
AU - Wijtmans, Maikel
AU - Vischer, Henry F.
AU - LEURS, R.
PY - 2025
DA - 2025/04/03
PB - Wiley
SP - 1307-1322
IS - 5
VL - 45
SN - 0198-6325
SN - 1098-1128
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Shi,
author = {Shuang Shi and Yangzhi Cao and Maikel Wijtmans and Henry F. Vischer and R. LEURS},
title = {Recent Developments in the Optical Control of Adrenergic Signaling},
journal = {Medicinal Research Reviews},
year = {2025},
volume = {45},
publisher = {Wiley},
month = {apr},
url = {https://onlinelibrary.wiley.com/doi/10.1002/med.22110},
number = {5},
pages = {1307--1322},
doi = {10.1002/med.22110}
}
MLA
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MLA Copy
Shi, Shuang, et al. “Recent Developments in the Optical Control of Adrenergic Signaling.” Medicinal Research Reviews, vol. 45, no. 5, Apr. 2025, pp. 1307-1322. https://onlinelibrary.wiley.com/doi/10.1002/med.22110.
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