Assessing and communicating heterogeneity of treatment effects for patient subpopulations: The hardest problem there is
1
Analytix Thinking, LLC Indianapolis Indiana USA
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Publication type: Journal Article
Publication date: 2021-03-03
scimago Q1
wos Q2
SJR: 1.074
CiteScore: 3.2
Impact factor: 1.4
ISSN: 15391604, 15391612
DOI:
10.1002/pst.2110
PubMed ID:
33655601
Pharmacology
Pharmacology (medical)
Statistics and Probability
Abstract
Heterogeneity is an enormously complex problem because there are so many dimensions and variables that can be considered when assessing which ones may influence an efficacy or safety outcome for an individual patient. This is difficult in randomized controlled trials and even more so in observational settings. An alternative approach is presented in which the individual patient becomes the subgroup, and similar patients are identified in the clinical trial database or electronic medical record that can be used to predict how that individual patient may respond to treatment.
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Total citations:
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Citations from 2024:
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(28.57%)
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MLA
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GOST
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Ruberg S. J. Assessing and communicating heterogeneity of treatment effects for patient subpopulations: The hardest problem there is // Pharmaceutical Statistics. 2021. Vol. 20. No. 5. pp. 939-944.
GOST all authors (up to 50)
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Ruberg S. J. Assessing and communicating heterogeneity of treatment effects for patient subpopulations: The hardest problem there is // Pharmaceutical Statistics. 2021. Vol. 20. No. 5. pp. 939-944.
Cite this
RIS
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TY - JOUR
DO - 10.1002/pst.2110
UR - https://doi.org/10.1002/pst.2110
TI - Assessing and communicating heterogeneity of treatment effects for patient subpopulations: The hardest problem there is
T2 - Pharmaceutical Statistics
AU - Ruberg, Stephen J.
PY - 2021
DA - 2021/03/03
PB - Wiley
SP - 939-944
IS - 5
VL - 20
PMID - 33655601
SN - 1539-1604
SN - 1539-1612
ER -
Cite this
BibTex (up to 50 authors)
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@article{2021_Ruberg,
author = {Stephen J. Ruberg},
title = {Assessing and communicating heterogeneity of treatment effects for patient subpopulations: The hardest problem there is},
journal = {Pharmaceutical Statistics},
year = {2021},
volume = {20},
publisher = {Wiley},
month = {mar},
url = {https://doi.org/10.1002/pst.2110},
number = {5},
pages = {939--944},
doi = {10.1002/pst.2110}
}
Cite this
MLA
Copy
Ruberg, Stephen J.. “Assessing and communicating heterogeneity of treatment effects for patient subpopulations: The hardest problem there is.” Pharmaceutical Statistics, vol. 20, no. 5, Mar. 2021, pp. 939-944. https://doi.org/10.1002/pst.2110.