Synthesis, Cytotoxicity, Pan‐HDAC Inhibitory Activity and Docking Study of N‐(2‐Aminophenyl)‐2‐arylquinoline‐4‐ and N‐(2‐Aminophenyl)‐2‐arylbenzo[h]quinoline‐4‐carboxamides**
Тип публикации: Journal Article
Дата публикации: 2022-08-01
General Chemistry
Краткое описание
In this study, we synthesized new series of N-(2-aminophenyl)-2-arylquinoline-4- and N-(2-aminophenyl)-2-arylbenzo[h]quinoline-4-carboxamide derivatives. Anticancer activity of the synthesized compounds was evaluated against A549, HT-29 and HCT116 cell lines. Pan-HDAC inhibitory activity evaluated on HT-29 and HCT116 cell lines. Docking study of the selected compounds was performed on HDAC isoforms.
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Omidkhah N. et al. Synthesis, Cytotoxicity, Pan‐HDAC Inhibitory Activity and Docking Study of N‐(2‐Aminophenyl)‐2‐arylquinoline‐4‐ and N‐(2‐Aminophenyl)‐2‐arylbenzo[h]quinoline‐4‐carboxamides** // ChemistrySelect. 2022. Vol. 7. No. 29.
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Omidkhah N., Eisvand F., Hadizadeh F., Zarghi A., Ghodsi R. Synthesis, Cytotoxicity, Pan‐HDAC Inhibitory Activity and Docking Study of N‐(2‐Aminophenyl)‐2‐arylquinoline‐4‐ and N‐(2‐Aminophenyl)‐2‐arylbenzo[h]quinoline‐4‐carboxamides** // ChemistrySelect. 2022. Vol. 7. No. 29.
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TY - JOUR
DO - 10.1002/slct.202201239
UR - https://doi.org/10.1002/slct.202201239
TI - Synthesis, Cytotoxicity, Pan‐HDAC Inhibitory Activity and Docking Study of N‐(2‐Aminophenyl)‐2‐arylquinoline‐4‐ and N‐(2‐Aminophenyl)‐2‐arylbenzo[h]quinoline‐4‐carboxamides**
T2 - ChemistrySelect
AU - Omidkhah, Negar
AU - Eisvand, Farhad
AU - Hadizadeh, Farzin
AU - Zarghi, Afshin
AU - Ghodsi, Razieh
PY - 2022
DA - 2022/08/01
PB - Wiley
IS - 29
VL - 7
SN - 2365-6549
ER -
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@article{2022_Omidkhah,
author = {Negar Omidkhah and Farhad Eisvand and Farzin Hadizadeh and Afshin Zarghi and Razieh Ghodsi},
title = {Synthesis, Cytotoxicity, Pan‐HDAC Inhibitory Activity and Docking Study of N‐(2‐Aminophenyl)‐2‐arylquinoline‐4‐ and N‐(2‐Aminophenyl)‐2‐arylbenzo[h]quinoline‐4‐carboxamides**},
journal = {ChemistrySelect},
year = {2022},
volume = {7},
publisher = {Wiley},
month = {aug},
url = {https://doi.org/10.1002/slct.202201239},
number = {29},
doi = {10.1002/slct.202201239}
}