volume 359 issue 4 pages 693-697

Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation

Publication typeJournal Article
Publication date2016-12-15
scimago Q1
wos Q1
SJR0.930
CiteScore8.0
Impact factor4.0
ISSN16154150, 16154169
General Chemistry
Abstract
We recently developed a novel Rh-catalyzed carbonylative benzannulation for the synthesis of indoles, benzofurans, and many related heterocycles. In this update, we demonstrated the utility of this method for the synthesis of several highly substituted benzofuran-containing natural products. The scope and limitation of the Rh-catalyzed carbonylative benzannulation was investigated in the context of natural product synthesis for the first time. This study also revealed the site-selectivity for Pd-catalyzed cross-coupling of substituted benzofurans. Two one-pot sequential cross-couplings were realized based on the observed site-selectivity. The strategy of preparing bicyclic heterocycles such as benzofurans by de novo synthesis of the benzene ring will find applications in many other related bioactive heterocycles.
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GOST Copy
Liu J. et al. Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation // Advanced Synthesis and Catalysis. 2016. Vol. 359. No. 4. pp. 693-697.
GOST all authors (up to 50) Copy
Liu J., Simmons C. J., Xie H., Yang F., Zhao X. L., Tang Yu., Tang W. Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation // Advanced Synthesis and Catalysis. 2016. Vol. 359. No. 4. pp. 693-697.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/adsc.201600992
UR - https://doi.org/10.1002/adsc.201600992
TI - Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation
T2 - Advanced Synthesis and Catalysis
AU - Liu, Jitian
AU - Simmons, Christopher J.
AU - Xie, Haibo
AU - Yang, Fan
AU - Zhao, Xian Liang
AU - Tang, Yu
AU - Tang, Weiping
PY - 2016
DA - 2016/12/15
PB - Wiley
SP - 693-697
IS - 4
VL - 359
SN - 1615-4150
SN - 1615-4169
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Liu,
author = {Jitian Liu and Christopher J. Simmons and Haibo Xie and Fan Yang and Xian Liang Zhao and Yu Tang and Weiping Tang},
title = {Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation},
journal = {Advanced Synthesis and Catalysis},
year = {2016},
volume = {359},
publisher = {Wiley},
month = {dec},
url = {https://doi.org/10.1002/adsc.201600992},
number = {4},
pages = {693--697},
doi = {10.1002/adsc.201600992}
}
MLA
Cite this
MLA Copy
Liu, Jitian, et al. “Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation.” Advanced Synthesis and Catalysis, vol. 359, no. 4, Dec. 2016, pp. 693-697. https://doi.org/10.1002/adsc.201600992.