Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease
Ian A Simpson
1
,
KOTESWARA R. CHUNDU
1
,
Theresa Davies-Hill
1
,
William G. Honer
2
,
P. C. W. Davies
2
Тип публикации: Journal Article
Дата публикации: 1994-05-01
scimago Q1
wos Q1
БС1
SJR: 3.736
CiteScore: 15.9
Impact factor: 7.7
ISSN: 03645134, 15318249
PubMed ID:
8179300
Neurology
Neurology (clinical)
Краткое описание
Glucose metabolism is depressed in the temporal and parietal regions of the cortex in patients with Alzheimer's disease. We measured the concentrations of two glucose transporters, GLUT1 and GLUT3, in six regions of brains from both control subjects and patients with Alzheimer's disease. The concentrations of both transporters were reduced in the cerebral cortex, with larger and highly significant reductions observed for GLUT3, the putative neuronal glucose transporter. The reductions in GLUT3 were greater than the loss of synapses, and should be considered as a potential cause of the deficits in glucose metabolism.
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ГОСТ
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Simpson I. A. et al. Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease // Annals of Neurology. 1994. Vol. 35. No. 5. pp. 546-551.
ГОСТ со всеми авторами (до 50)
Скопировать
Simpson I. A., CHUNDU K. R., Davies-Hill T., Honer W. G., Davies P. C. W. Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease // Annals of Neurology. 1994. Vol. 35. No. 5. pp. 546-551.
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RIS
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TY - JOUR
DO - 10.1002/ana.410350507
UR - https://doi.org/10.1002/ana.410350507
TI - Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease
T2 - Annals of Neurology
AU - Simpson, Ian A
AU - CHUNDU, KOTESWARA R.
AU - Davies-Hill, Theresa
AU - Honer, William G.
AU - Davies, P. C. W.
PY - 1994
DA - 1994/05/01
PB - Wiley
SP - 546-551
IS - 5
VL - 35
PMID - 8179300
SN - 0364-5134
SN - 1531-8249
ER -
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BibTex (до 50 авторов)
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@article{1994_Simpson,
author = {Ian A Simpson and KOTESWARA R. CHUNDU and Theresa Davies-Hill and William G. Honer and P. C. W. Davies},
title = {Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease},
journal = {Annals of Neurology},
year = {1994},
volume = {35},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002/ana.410350507},
number = {5},
pages = {546--551},
doi = {10.1002/ana.410350507}
}
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MLA
Скопировать
Simpson, Ian A., et al. “Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease.” Annals of Neurology, vol. 35, no. 5, May. 1994, pp. 546-551. https://doi.org/10.1002/ana.410350507.