volume 35 issue 5 pages 546-551

Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease

Publication typeJournal Article
Publication date1994-05-01
scimago Q1
wos Q1
SJR3.736
CiteScore15.9
Impact factor7.7
ISSN03645134, 15318249
PubMed ID:  8179300
Neurology
Neurology (clinical)
Abstract
Glucose metabolism is depressed in the temporal and parietal regions of the cortex in patients with Alzheimer's disease. We measured the concentrations of two glucose transporters, GLUT1 and GLUT3, in six regions of brains from both control subjects and patients with Alzheimer's disease. The concentrations of both transporters were reduced in the cerebral cortex, with larger and highly significant reductions observed for GLUT3, the putative neuronal glucose transporter. The reductions in GLUT3 were greater than the loss of synapses, and should be considered as a potential cause of the deficits in glucose metabolism.
Found 
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GOST |
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GOST Copy
Simpson I. A. et al. Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease // Annals of Neurology. 1994. Vol. 35. No. 5. pp. 546-551.
GOST all authors (up to 50) Copy
Simpson I. A., CHUNDU K. R., Davies-Hill T., Honer W. G., Davies P. C. W. Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease // Annals of Neurology. 1994. Vol. 35. No. 5. pp. 546-551.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/ana.410350507
UR - https://doi.org/10.1002/ana.410350507
TI - Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease
T2 - Annals of Neurology
AU - Simpson, Ian A
AU - CHUNDU, KOTESWARA R.
AU - Davies-Hill, Theresa
AU - Honer, William G.
AU - Davies, P. C. W.
PY - 1994
DA - 1994/05/01
PB - Wiley
SP - 546-551
IS - 5
VL - 35
PMID - 8179300
SN - 0364-5134
SN - 1531-8249
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{1994_Simpson,
author = {Ian A Simpson and KOTESWARA R. CHUNDU and Theresa Davies-Hill and William G. Honer and P. C. W. Davies},
title = {Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease},
journal = {Annals of Neurology},
year = {1994},
volume = {35},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002/ana.410350507},
number = {5},
pages = {546--551},
doi = {10.1002/ana.410350507}
}
MLA
Cite this
MLA Copy
Simpson, Ian A., et al. “Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease.” Annals of Neurology, vol. 35, no. 5, May. 1994, pp. 546-551. https://doi.org/10.1002/ana.410350507.