Structure Elucidation and Characterization of Different Thyroxine Polymorphs
Publication type: Journal Article
Publication date: 2015-07-24
scimago Q1
wos Q1
SJR: 5.550
CiteScore: 27.6
Impact factor: 16.9
ISSN: 14337851, 15213773
PubMed ID:
26213168
General Chemistry
Catalysis
Abstract
Thyroid hormones regulate almost every process in the body, including body temperature, growth, and heart rate. They influence carbohydrate metabolism, protein synthesis and breakdown, and cardiovascular, renal, and brain function. Two new polymorphs of synthetic L-thyroxine (T4) are reported and the effect of polymorphism on the solubility of this important hormone is shown. Conformational changes were also discovered to have a remarkable effect on the strength of halogen bonding and the reactivity of the C-I bonds, which could have a significant effect on the hormone activity.
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Metrics
38
Total citations:
38
Citations from 2024:
6
(15.79%)
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GOST
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Mondal S., Mugesh G. Structure Elucidation and Characterization of Different Thyroxine Polymorphs // Angewandte Chemie - International Edition. 2015. Vol. 54. No. 37. pp. 10833-10837.
GOST all authors (up to 50)
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Mondal S., Mugesh G. Structure Elucidation and Characterization of Different Thyroxine Polymorphs // Angewandte Chemie - International Edition. 2015. Vol. 54. No. 37. pp. 10833-10837.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/anie.201505281
UR - https://doi.org/10.1002/anie.201505281
TI - Structure Elucidation and Characterization of Different Thyroxine Polymorphs
T2 - Angewandte Chemie - International Edition
AU - Mondal, Santanu
AU - Mugesh, Govindasamy
PY - 2015
DA - 2015/07/24
PB - Wiley
SP - 10833-10837
IS - 37
VL - 54
PMID - 26213168
SN - 1433-7851
SN - 1521-3773
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2015_Mondal,
author = {Santanu Mondal and Govindasamy Mugesh},
title = {Structure Elucidation and Characterization of Different Thyroxine Polymorphs},
journal = {Angewandte Chemie - International Edition},
year = {2015},
volume = {54},
publisher = {Wiley},
month = {jul},
url = {https://doi.org/10.1002/anie.201505281},
number = {37},
pages = {10833--10837},
doi = {10.1002/anie.201505281}
}
Cite this
MLA
Copy
Mondal, Santanu, and Govindasamy Mugesh. “Structure Elucidation and Characterization of Different Thyroxine Polymorphs.” Angewandte Chemie - International Edition, vol. 54, no. 37, Jul. 2015, pp. 10833-10837. https://doi.org/10.1002/anie.201505281.