Journal of Applied Polymer Science

, volume 138 , issue 2 , pages 49662

Highly filled poly( l ‐lactic acid)/hydroxyapatite composite for 3D printing of personalized bone tissue engineering scaffolds

Gleb E Dubinenko ¹

Gleb Dubinenko ²

Aleksey Zinoviev ^{1, 2}

E. N. Bolbasov ^{1, 3}

Evgeny Bolbasov ^{2, 4}

Anna Kozelskaya ¹

Evgeniy Shesterikov ^{3, 4}

Victor Novikov ^{1, 2}

S. I. Tverdokhlebov ^{1, 2}

Hide authors affiliations Show authors affiliations: 4 affiliations

Tomsk Polytechnic University Tomsk Russia |

V.E. Zuev Institute of Atmospheric Optics SB RAS Tomsk Russia |

⁴

V.E. Zuev Institute of Atmospheric Optics SB RAS Tomsk Russia |

Publication type: Journal Article

Publication date: 2020-07-27

Wiley

Journal of Applied Polymer Science

scimago Q2

wos Q3

SJR: 0.572

CiteScore: 5.8

Impact factor: 2.8

ISSN: 00218995, 10974628

DOI: 10.1002/app.49662

Copy DOI

Materials Chemistry

Surfaces, Coatings and Films

General Chemistry

Polymers and Plastics

Abstract

The designing of new biodegradable polymer composites is one of the most promising areas of modern orthopedics and regenerative surgery. At present, a number of methods have been proposed for designing and processing biodegradable polymer composites via various 3D printing technologies; however, the homogeneity of filler distribution together with mechanical properties of scaffolds made of such composites are far from those required for clinical use. In this study, the method for producing biodegradable composite material based on poly(l‐lactic acid) (PLLA) solution in organic solvent and hydroxyapatite (HAp) powder was proposed. The influence of HAp weight fraction and additional annealing on PLLA matrix crystallinity was investigated. It was shown that crystallinity of PLLA decreases from 58.84 ± 1.21 to 17.33 ± 1.69 as HAp weight fraction increased from 0 to 50 wt%. However, HAp filler promoted PLLA crystallites growth according to the X‐ray powder diffraction analysis. The results of nanoindentation showed Young's modulus values of the 3D‐printed scaffolds with 50 wt% of HAp at the level of human femur and tibia.

Found

2 citations

Demina Tatiana

🤝

DSc in Chemistry, associate professor

78 publications, 865 citations

h-index: 17

Moscow Aviation Institute (National Research University)

Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences

Sechenov First Moscow State Medical University

Nature-like technologies

1 citation

Akopova Tatiana

81 publications, 1 016 citations, 20 reviews

h-index: 19

Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences

1 citation

Pariy Igor

🤝

13 publications, 566 citations

h-index: 12

National Research Tomsk Polytechnic University

1 citation

Popyrina Tatiana

🤝

PhD in Chemistry

17 publications, 134 citations, 13 reviews

h-index: 8

Moscow Aviation Institute (National Research University)

Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences

A.N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences

1 citation

Khavpachev Mukhamed

PhD in Chemistry

10 publications, 78 citations

h-index: 5

Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences

Top-30

Journals

	1 2 3 4
Polymers	Polymers, 4, 11.11% Polymers 4 publications, 11.11%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 2, 5.56% International Journal of Molecular Sciences 2 publications, 5.56%
Polymer	Polymer, 2, 5.56% Polymer 2 publications, 5.56%
ACS Biomaterials Science and Engineering	ACS Biomaterials Science and Engineering, 2, 5.56% ACS Biomaterials Science and Engineering 2 publications, 5.56%
Journal of Materials Science	Journal of Materials Science, 1, 2.78% Journal of Materials Science 1 publication, 2.78%
Bioengineering	Bioengineering, 1, 2.78% Bioengineering 1 publication, 2.78%
Current Reviews in Musculoskeletal Medicine	Current Reviews in Musculoskeletal Medicine, 1, 2.78% Current Reviews in Musculoskeletal Medicine 1 publication, 2.78%
Polymer Journal	Polymer Journal, 1, 2.78% Polymer Journal 1 publication, 2.78%
International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 1, 2.78% International Journal of Biological Macromolecules 1 publication, 2.78%
Asian Journal of Pharmaceutical Sciences	Asian Journal of Pharmaceutical Sciences, 1, 2.78% Asian Journal of Pharmaceutical Sciences 1 publication, 2.78%
Materials Science and Engineering C	Materials Science and Engineering C, 1, 2.78% Materials Science and Engineering C 1 publication, 2.78%
Journal of the Mechanical Behavior of Biomedical Materials	Journal of the Mechanical Behavior of Biomedical Materials, 1, 2.78% Journal of the Mechanical Behavior of Biomedical Materials 1 publication, 2.78%
Nanobiotechnology Reports	Nanobiotechnology Reports, 1, 2.78% Nanobiotechnology Reports 1 publication, 2.78%
Chemical Reviews	Chemical Reviews, 1, 2.78% Chemical Reviews 1 publication, 2.78%
Journal of Materials Chemistry B	Journal of Materials Chemistry B, 1, 2.78% Journal of Materials Chemistry B 1 publication, 2.78%
Journal of Applied Polymer Science	Journal of Applied Polymer Science, 1, 2.78% Journal of Applied Polymer Science 1 publication, 2.78%
Nanomaterials	Nanomaterials, 1, 2.78% Nanomaterials 1 publication, 2.78%
Polymer Science - Series A	Polymer Science - Series A, 1, 2.78% Polymer Science - Series A 1 publication, 2.78%
Acta Biomaterialia	Acta Biomaterialia, 1, 2.78% Acta Biomaterialia 1 publication, 2.78%
Macromolecular Chemistry and Physics	Macromolecular Chemistry and Physics, 1, 2.78% Macromolecular Chemistry and Physics 1 publication, 2.78%
Opuholi Golovy i Sei	Opuholi Golovy i Sei, 1, 2.78% Opuholi Golovy i Sei 1 publication, 2.78%
Results in Surfaces and Interfaces	Results in Surfaces and Interfaces, 1, 2.78% Results in Surfaces and Interfaces 1 publication, 2.78%
Ceramics International	Ceramics International, 1, 2.78% Ceramics International 1 publication, 2.78%
Journal of Clinical Medicine	Journal of Clinical Medicine, 1, 2.78% Journal of Clinical Medicine 1 publication, 2.78%
European Journal of Pharmaceutics and Biopharmaceutics	European Journal of Pharmaceutics and Biopharmaceutics, 1, 2.78% European Journal of Pharmaceutics and Biopharmaceutics 1 publication, 2.78%
Biofabrication	Biofabrication, 1, 2.78% Biofabrication 1 publication, 2.78%
Biomimetics	Biomimetics, 1, 2.78% Biomimetics 1 publication, 2.78%
	1 2 3 4

Publishers

	2 4 6 8 10 12
Elsevier	Elsevier, 12, 33.33% Elsevier 12 publications, 33.33%
MDPI	MDPI, 10, 27.78% MDPI 10 publications, 27.78%
Springer Nature	Springer Nature, 3, 8.33% Springer Nature 3 publications, 8.33%
American Chemical Society (ACS)	American Chemical Society (ACS), 3, 8.33% American Chemical Society (ACS) 3 publications, 8.33%
Pleiades Publishing	Pleiades Publishing, 2, 5.56% Pleiades Publishing 2 publications, 5.56%
Wiley	Wiley, 2, 5.56% Wiley 2 publications, 5.56%
Shenyang Pharmaceutical University	Shenyang Pharmaceutical University, 1, 2.78% Shenyang Pharmaceutical University 1 publication, 2.78%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 2.78% Royal Society of Chemistry (RSC) 1 publication, 2.78%
Publishing House ABV Press	Publishing House ABV Press, 1, 2.78% Publishing House ABV Press 1 publication, 2.78%
IOP Publishing	IOP Publishing, 1, 2.78% IOP Publishing 1 publication, 2.78%
	2 4 6 8 10 12

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

Metrics

Cite this

GOST |

Cite this

GOST Copy

Dubinenko G. E. et al. Highly filled poly( l ‐lactic acid)/hydroxyapatite composite for 3D printing of personalized bone tissue engineering scaffolds // Journal of Applied Polymer Science. 2020. Vol. 138. No. 2. p. 49662.

GOST all authors (up to 50) Copy

Dubinenko G. E., Dubinenko G., Zinoviev A., Bolbasov E. N., Bolbasov E., Kozelskaya A., Shesterikov E., Novikov V., Tverdokhlebov S. I. Highly filled poly( l ‐lactic acid)/hydroxyapatite composite for 3D printing of personalized bone tissue engineering scaffolds // Journal of Applied Polymer Science. 2020. Vol. 138. No. 2. p. 49662.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1002/app.49662

UR - https://onlinelibrary.wiley.com/doi/10.1002/app.49662

TI - Highly filled poly( l ‐lactic acid)/hydroxyapatite composite for 3D printing of personalized bone tissue engineering scaffolds

T2 - Journal of Applied Polymer Science

AU - Dubinenko, Gleb E

AU - Dubinenko, Gleb

AU - Zinoviev, Aleksey

AU - Bolbasov, E. N.

AU - Bolbasov, Evgeny

AU - Kozelskaya, Anna

AU - Shesterikov, Evgeniy

AU - Novikov, Victor

AU - Tverdokhlebov, S. I.

PY - 2020

DA - 2020/07/27

PB - Wiley

SP - 49662

IS - 2

VL - 138

SN - 0021-8995

SN - 1097-4628

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2020_Dubinenko,

author = {Gleb E Dubinenko and Gleb Dubinenko and Aleksey Zinoviev and E. N. Bolbasov and Evgeny Bolbasov and Anna Kozelskaya and Evgeniy Shesterikov and Victor Novikov and S. I. Tverdokhlebov},

title = {Highly filled poly( l ‐lactic acid)/hydroxyapatite composite for 3D printing of personalized bone tissue engineering scaffolds},

journal = {Journal of Applied Polymer Science},

year = {2020},

volume = {138},

publisher = {Wiley},

month = {jul},

url = {https://onlinelibrary.wiley.com/doi/10.1002/app.49662},

number = {2},

pages = {49662},

doi = {10.1002/app.49662}

}

MLA

Cite this

MLA Copy

Dubinenko, Gleb E., et al. “Highly filled poly( l ‐lactic acid)/hydroxyapatite composite for 3D printing of personalized bone tissue engineering scaffolds.” Journal of Applied Polymer Science, vol. 138, no. 2, Jul. 2020, p. 49662. https://onlinelibrary.wiley.com/doi/10.1002/app.49662.

Publisher

Wiley

Journal

Journal of Applied Polymer Science

scimago Q2

wos Q3

SJR

0.572

CiteScore

5.8

Impact factor

2.8

ISSN

00218995 (Print)

10974628 (Electronic)

Profiles