Wiley
Archiv der Pharmazie
,  том 343 ,  издание 5

Synthesis andin-vitroCytotoxic Evaluation of Novel Pyridazin-4-one Derivatives

Тип публикации: Journal Article
Дата публикации: 2010-03-10
Wiley
scimago Q2
wos Q2
БС2
SJR: 0.571
CiteScore: 7
Impact factor: 3.6
ISSN: 03656233, 15214184
Drug Discovery
Pharmaceutical Science
Краткое описание
A new series of N-aryl-4-oxo-1,4-dihydro-pyridazine-3-carboxylic acids has been synthesized by condensation of aryldiazonium with 4-hydroxy-6-methyl-2-pyrone. Some of these compounds exhibited in-vitro cytotoxic activity with moderate to excellent growth inhibition against the murine P815 mastocytoma cell line. Compound 5b showed an important cytotoxic activity against cell line P815 (IC50 = 0.40 μg/mL).
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Mojahidi S. et al. Synthesis andin-vitroCytotoxic Evaluation of Novel Pyridazin-4-one Derivatives // Archiv der Pharmazie. 2010. Vol. 343. No. 5.
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Mojahidi S., Sekkak H., Abouricha S., Benchat N., Mousse H. A., ZYAD A. Synthesis andin-vitroCytotoxic Evaluation of Novel Pyridazin-4-one Derivatives // Archiv der Pharmazie. 2010. Vol. 343. No. 5.
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TY - JOUR
DO - 10.1002/ardp.200900290
UR - https://doi.org/10.1002/ardp.200900290
TI - Synthesis andin-vitroCytotoxic Evaluation of Novel Pyridazin-4-one Derivatives
T2 - Archiv der Pharmazie
AU - Mojahidi, Souad
AU - Sekkak, Hanan
AU - Abouricha, Said
AU - Benchat, Nouredine
AU - Mousse, Hassan Ait
AU - ZYAD, ABDELMAJID
PY - 2010
DA - 2010/03/10
PB - Wiley
IS - 5
VL - 343
PMID - 20222064
SN - 0365-6233
SN - 1521-4184
ER -
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@article{2010_Mojahidi,
author = {Souad Mojahidi and Hanan Sekkak and Said Abouricha and Nouredine Benchat and Hassan Ait Mousse and ABDELMAJID ZYAD},
title = {Synthesis andin-vitroCytotoxic Evaluation of Novel Pyridazin-4-one Derivatives},
journal = {Archiv der Pharmazie},
year = {2010},
volume = {343},
publisher = {Wiley},
month = {mar},
url = {https://doi.org/10.1002/ardp.200900290},
number = {5},
doi = {10.1002/ardp.200900290}
}