Stereoselective Crystallization as a Basis for Single-Enantiomer Drug Production
Тип публикации: Journal Article
Дата публикации: 2017-05-31
scimago Q2
wos Q3
БС2
SJR: 0.374
CiteScore: 3.6
Impact factor: 1.6
ISSN: 09307516, 15214125
General Chemistry
General Chemical Engineering
Industrial and Manufacturing Engineering
Краткое описание
In the XXI century, single enantiomeric chiral active pharmaceutical ingredients (APIs) prevail among new drugs. Their preparation is made easier by using direct methods for the separation of racemates. This review summarises the history of the issue, provides information about new and updated methods of conglomerate identification and practical implementation options for direct resolutions. Examples are given of the use of direct methods for obtaining enantiopure APIs by the resolution of their racemic synthetic precursors, using a slight modification of the target product and finally by direct resolution of the racemic chiral drugs as such.
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ГОСТ
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Bredikhin A. A., Bredikhina Z. A. Stereoselective Crystallization as a Basis for Single-Enantiomer Drug Production // Chemical Engineering and Technology. 2017. Vol. 40. No. 7. pp. 1211-1220.
ГОСТ со всеми авторами (до 50)
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Bredikhin A. A., Bredikhina Z. A. Stereoselective Crystallization as a Basis for Single-Enantiomer Drug Production // Chemical Engineering and Technology. 2017. Vol. 40. No. 7. pp. 1211-1220.
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RIS
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TY - JOUR
DO - 10.1002/ceat.201600649
UR - https://doi.org/10.1002/ceat.201600649
TI - Stereoselective Crystallization as a Basis for Single-Enantiomer Drug Production
T2 - Chemical Engineering and Technology
AU - Bredikhin, Alexander A.
AU - Bredikhina, Zemfira A.
PY - 2017
DA - 2017/05/31
PB - Wiley
SP - 1211-1220
IS - 7
VL - 40
SN - 0930-7516
SN - 1521-4125
ER -
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BibTex (до 50 авторов)
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@article{2017_Bredikhin,
author = {Alexander A. Bredikhin and Zemfira A. Bredikhina},
title = {Stereoselective Crystallization as a Basis for Single-Enantiomer Drug Production},
journal = {Chemical Engineering and Technology},
year = {2017},
volume = {40},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002/ceat.201600649},
number = {7},
pages = {1211--1220},
doi = {10.1002/ceat.201600649}
}
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MLA
Скопировать
Bredikhin, Alexander A., and Zemfira A. Bredikhina. “Stereoselective Crystallization as a Basis for Single-Enantiomer Drug Production.” Chemical Engineering and Technology, vol. 40, no. 7, May. 2017, pp. 1211-1220. https://doi.org/10.1002/ceat.201600649.