volume 19 issue 21 pages 6586-6590

Duality of donor-acceptor cyclopropane reactivity as a three-carbon component in five-membered ring construction: [3+2] annulation versus [3+2] cycloaddition

Publication typeJournal Article
Publication date2013-04-09
scimago Q1
wos Q2
SJR0.981
CiteScore6.7
Impact factor3.7
ISSN09476539, 15213765
General Chemistry
Catalysis
Organic Chemistry
Abstract
Quo vadis? The Lewis acid catalyzed reaction of (hetero)aryl-derived donor-acceptor cyclopropanes with alkenes can be selectively directed along a [3+2] annulation pathway (see scheme). This new process provides convenient and efficient access to indanes and other cyclopentannulated (hetero)arenes, among which polyoxygenated 1-arylindanes exhibit significant cytotoxicity against several cancer cell lines with an IC50 of 10(-6)-10(-5)  M.
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Volkova Y. et al. Duality of donor-acceptor cyclopropane reactivity as a three-carbon component in five-membered ring construction: [3+2] annulation versus [3+2] cycloaddition // Chemistry - A European Journal. 2013. Vol. 19. No. 21. pp. 6586-6590.
GOST all authors (up to 50) Copy
Volkova Y., Budynina E. M., Kaplun A. E., Ivanova O., Chagarovskiy A. O., Skvortsov D., Rybakov V. B., Trushkov I. V., Melnikov M. Y. Duality of donor-acceptor cyclopropane reactivity as a three-carbon component in five-membered ring construction: [3+2] annulation versus [3+2] cycloaddition // Chemistry - A European Journal. 2013. Vol. 19. No. 21. pp. 6586-6590.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/chem.201300731
UR - https://doi.org/10.1002/chem.201300731
TI - Duality of donor-acceptor cyclopropane reactivity as a three-carbon component in five-membered ring construction: [3+2] annulation versus [3+2] cycloaddition
T2 - Chemistry - A European Journal
AU - Volkova, Yulia
AU - Budynina, Ekaterina M
AU - Kaplun, Alexey E
AU - Ivanova, Olga
AU - Chagarovskiy, Alexey O
AU - Skvortsov, Dmitry
AU - Rybakov, Victor B.
AU - Trushkov, Igor V
AU - Melnikov, Mikhail Y.
PY - 2013
DA - 2013/04/09
PB - Wiley
SP - 6586-6590
IS - 21
VL - 19
PMID - 23576404
SN - 0947-6539
SN - 1521-3765
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2013_Volkova,
author = {Yulia Volkova and Ekaterina M Budynina and Alexey E Kaplun and Olga Ivanova and Alexey O Chagarovskiy and Dmitry Skvortsov and Victor B. Rybakov and Igor V Trushkov and Mikhail Y. Melnikov},
title = {Duality of donor-acceptor cyclopropane reactivity as a three-carbon component in five-membered ring construction: [3+2] annulation versus [3+2] cycloaddition},
journal = {Chemistry - A European Journal},
year = {2013},
volume = {19},
publisher = {Wiley},
month = {apr},
url = {https://doi.org/10.1002/chem.201300731},
number = {21},
pages = {6586--6590},
doi = {10.1002/chem.201300731}
}
MLA
Cite this
MLA Copy
Volkova, Yulia, et al. “Duality of donor-acceptor cyclopropane reactivity as a three-carbon component in five-membered ring construction: [3+2] annulation versus [3+2] cycloaddition.” Chemistry - A European Journal, vol. 19, no. 21, Apr. 2013, pp. 6586-6590. https://doi.org/10.1002/chem.201300731.