volume 22 issue 26 pages 8777-8780

Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones

John T R Liddon 1
Michael J James 1
Aimee K Clarke 1
Peter O’Brien 1
R. Taylor 1
William P. Unsworth 1
Publication typeJournal Article
Publication date2016-05-19
scimago Q1
wos Q2
SJR0.981
CiteScore6.7
Impact factor3.7
ISSN09476539, 15213765
General Chemistry
Catalysis
Organic Chemistry
Abstract
Medicinally relevant spirocyclic indolenines, carbazoles and quinolines can each be directly synthesised selectively from common indolyl ynone starting materials by catalyst variation. The high yielding, divergent reactions all proceed by an initial dearomatising spirocyclisation reaction to generate an intermediate vinyl-metal species, which then rearranges selectively by careful choice of catalyst and reaction conditions.
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GOST Copy
Liddon J. T. R. et al. Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones // Chemistry - A European Journal. 2016. Vol. 22. No. 26. pp. 8777-8780.
GOST all authors (up to 50) Copy
Liddon J. T. R., James M. J., Clarke A. K., O’Brien P., Taylor R., Unsworth W. P. Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones // Chemistry - A European Journal. 2016. Vol. 22. No. 26. pp. 8777-8780.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1002/chem.201601836
UR - https://doi.org/10.1002/chem.201601836
TI - Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones
T2 - Chemistry - A European Journal
AU - Liddon, John T R
AU - James, Michael J
AU - Clarke, Aimee K
AU - O’Brien, Peter
AU - Taylor, R.
AU - Unsworth, William P.
PY - 2016
DA - 2016/05/19
PB - Wiley
SP - 8777-8780
IS - 26
VL - 22
PMID - 27124236
SN - 0947-6539
SN - 1521-3765
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Liddon,
author = {John T R Liddon and Michael J James and Aimee K Clarke and Peter O’Brien and R. Taylor and William P. Unsworth},
title = {Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones},
journal = {Chemistry - A European Journal},
year = {2016},
volume = {22},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002/chem.201601836},
number = {26},
pages = {8777--8780},
doi = {10.1002/chem.201601836}
}
MLA
Cite this
MLA Copy
Liddon, John T. R., et al. “Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones.” Chemistry - A European Journal, vol. 22, no. 26, May. 2016, pp. 8777-8780. https://doi.org/10.1002/chem.201601836.