Chemistry - A European Journal, volume 23, issue 6, pages 1231-1236

Intramolecular Parallel [4+3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]Decane and Corresponding Polycyclic Skeletons

Publication typeJournal Article
Publication date2016-12-29
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.3
ISSN09476539, 15213765
General Chemistry
Catalysis
Organic Chemistry
Abstract
Aiming to develop efficient and general strategies for construction of complex and diverse polycyclic skeletons, we have successfully developed [4+3]IMPC (intramolecular parallel cycloaddition) of cyclopropane 1,1-diesters with [3]dendralenes. With a combination of the [4+3]IMPC and subsequent [4+n] cycloadditions, trans-[5.3.0]decane skeleton and its corresponding structurally complex and diverse polycyclic variants could be constructed efficiently. This novel [4+3] cycloaddition reaction mode of donor-acceptor cyclopropanes proceeds as a result of the ring-strain relief of a trans-[3.3.0]octane. We strongly believe that the developed methods will demonstrate potential applications in natural products synthesis and drug discovery.

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GOST |
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GOST Copy
Zhang C. et al. Intramolecular Parallel [4+3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]Decane and Corresponding Polycyclic Skeletons // Chemistry - A European Journal. 2016. Vol. 23. No. 6. pp. 1231-1236.
GOST all authors (up to 50) Copy
Zhang C., Tian J., Ren J., Wang Z. Intramolecular Parallel [4+3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]Decane and Corresponding Polycyclic Skeletons // Chemistry - A European Journal. 2016. Vol. 23. No. 6. pp. 1231-1236.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1002/chem.201605190
UR - https://doi.org/10.1002/chem.201605190
TI - Intramolecular Parallel [4+3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]Decane and Corresponding Polycyclic Skeletons
T2 - Chemistry - A European Journal
AU - Tian, Jun
AU - Ren, Jun
AU - Zhang, Chi
AU - Wang, Zhong-Wen
PY - 2016
DA - 2016/12/29 00:00:00
PB - Wiley
SP - 1231-1236
IS - 6
VL - 23
SN - 0947-6539
SN - 1521-3765
ER -
BibTex |
Cite this
BibTex Copy
@article{2016_Zhang,
author = {Jun Tian and Jun Ren and Chi Zhang and Zhong-Wen Wang},
title = {Intramolecular Parallel [4+3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]Decane and Corresponding Polycyclic Skeletons},
journal = {Chemistry - A European Journal},
year = {2016},
volume = {23},
publisher = {Wiley},
month = {dec},
url = {https://doi.org/10.1002/chem.201605190},
number = {6},
pages = {1231--1236},
doi = {10.1002/chem.201605190}
}
MLA
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MLA Copy
Zhang, Chi, et al. “Intramolecular Parallel [4+3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]Decane and Corresponding Polycyclic Skeletons.” Chemistry - A European Journal, vol. 23, no. 6, Dec. 2016, pp. 1231-1236. https://doi.org/10.1002/chem.201605190.
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