Chemistry - A European Journal, volume 29, issue 55

Robust Biosensor Based on Carbon Nanotubes/Protein Hybrid Electrolyte Gated Transistors

Alessandro Paradisi 1
Marcello Berto 1
Matteo Di Giosia 2
Sara Mazzali 1
Marco Borsari 3
Tainah Dorina Marforio 2
F. Zerbetto 2
Matteo Calvaresi 2
Anna Orieshyna 4
Nadav Amdursky 4
Carlo Bortolotti 1
F. Biscarini 1, 5
Publication typeJournal Article
Publication date2023-08-31
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.3
ISSN09476539, 15213765
General Chemistry
Catalysis
Organic Chemistry
Abstract

Semiconducting single walled carbon nanotubes (SWCNTs) are promising materials for biosensing applications with electrolyte‐gated transistors (EGT). However, to be employed in EGT devices, SWCNTs often require lengthy solution‐processing fabrication techniques. Here, we introduce a simple solution‐based method that allows fabricating EGT devices from stable dispersions of SWCNTs/bovine serum albumin (BSA) hybrids in water. The dispersion is then deposited on a substrate allowing the formation of a SWCNTs random network as the semiconducting channel. We demonstrate that this methodology allows the fabrication of EGT devices with electric performances that allow their use in biosensing applications. We demonstrate their application for the detection of cortisol in solution, upon gate electrode functionalization with anti‐cortisol antibodies. This is a robust and cost‐effective methodology that sets the ground for a SWCNT/BSA‐based biosensing platform that allows overcoming many limitations of standard SWCNTs biosensor fabrications.

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Paradisi A. et al. Robust Biosensor Based on Carbon Nanotubes/Protein Hybrid Electrolyte Gated Transistors // Chemistry - A European Journal. 2023. Vol. 29. No. 55.
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Paradisi A., Berto M., Di Giosia M., Mazzali S., Borsari M., Marforio T. D., Zerbetto F., Calvaresi M., Orieshyna A., Amdursky N., Bortolotti C., Biscarini F. Robust Biosensor Based on Carbon Nanotubes/Protein Hybrid Electrolyte Gated Transistors // Chemistry - A European Journal. 2023. Vol. 29. No. 55.
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RIS Copy
TY - JOUR
DO - 10.1002/chem.202301704
UR - https://doi.org/10.1002/chem.202301704
TI - Robust Biosensor Based on Carbon Nanotubes/Protein Hybrid Electrolyte Gated Transistors
T2 - Chemistry - A European Journal
AU - Paradisi, Alessandro
AU - Berto, Marcello
AU - Di Giosia, Matteo
AU - Mazzali, Sara
AU - Borsari, Marco
AU - Marforio, Tainah Dorina
AU - Zerbetto, F.
AU - Calvaresi, Matteo
AU - Orieshyna, Anna
AU - Amdursky, Nadav
AU - Bortolotti, Carlo
AU - Biscarini, F.
PY - 2023
DA - 2023/08/31 00:00:00
PB - Wiley
IS - 55
VL - 29
SN - 0947-6539
SN - 1521-3765
ER -
BibTex
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BibTex Copy
@article{2023_Paradisi,
author = {Alessandro Paradisi and Marcello Berto and Matteo Di Giosia and Sara Mazzali and Marco Borsari and Tainah Dorina Marforio and F. Zerbetto and Matteo Calvaresi and Anna Orieshyna and Nadav Amdursky and Carlo Bortolotti and F. Biscarini},
title = {Robust Biosensor Based on Carbon Nanotubes/Protein Hybrid Electrolyte Gated Transistors},
journal = {Chemistry - A European Journal},
year = {2023},
volume = {29},
publisher = {Wiley},
month = {aug},
url = {https://doi.org/10.1002/chem.202301704},
number = {55},
doi = {10.1002/chem.202301704}
}
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