том 4 издание 3 страницы 325-328

The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection

Тип публикацииJournal Article
Дата публикации2009-03-16
scimago Q1
wos Q2
БС2
SJR0.717
CiteScore6.7
Impact factor3.4
ISSN18607179, 18607187
Organic Chemistry
Drug Discovery
Biochemistry
Pharmacology
Molecular Medicine
General Pharmacology, Toxicology and Pharmaceutics
Краткое описание
Blue makes it happen: The non-uniform charge distribution of the blue colored azulene framework is highly suitable for the bioisosteric replacement of bicyclic heteroarene moieties. Showing an analogous binding mode as heterocyclic dopamine D4 receptor-selective lead compounds, the induction of penile erection in rats over a greater range of doses indicates a putative advantage of the rationally developed azulene derivative 2 b over apomorphine.
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ГОСТ |
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Löber S. et al. The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection // ChemMedChem. 2009. Vol. 4. No. 3. pp. 325-328.
ГОСТ со всеми авторами (до 50) Скопировать
Löber S., Tschammer N., Hübner H., Melis M. G., Argiolas A., Niv M. Y. The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection // ChemMedChem. 2009. Vol. 4. No. 3. pp. 325-328.
RIS |
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TY - JOUR
DO - 10.1002/cmdc.200800395
UR - https://doi.org/10.1002/cmdc.200800395
TI - The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection
T2 - ChemMedChem
AU - Löber, Stefan
AU - Tschammer, Nuska
AU - Hübner, Harald
AU - Melis, Maria G.
AU - Argiolas, Antonio
AU - Niv, Masha Y.
PY - 2009
DA - 2009/03/16
PB - Wiley
SP - 325-328
IS - 3
VL - 4
PMID - 19185034
SN - 1860-7179
SN - 1860-7187
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2009_Löber,
author = {Stefan Löber and Nuska Tschammer and Harald Hübner and Maria G. Melis and Antonio Argiolas and Masha Y. Niv},
title = {The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection},
journal = {ChemMedChem},
year = {2009},
volume = {4},
publisher = {Wiley},
month = {mar},
url = {https://doi.org/10.1002/cmdc.200800395},
number = {3},
pages = {325--328},
doi = {10.1002/cmdc.200800395}
}
MLA
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Löber, Stefan, et al. “The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection.” ChemMedChem, vol. 4, no. 3, Mar. 2009, pp. 325-328. https://doi.org/10.1002/cmdc.200800395.