volume 15 issue 15 pages 1490-1496

Surface Modification of Luminescent Ln III Fluoride Core–Shell Nanoparticles with Acetylsalicylic acid (Aspirin): Synthesis, Spectroscopic and in Vitro Hemocompatibility Studies

Publication typeJournal Article
Publication date2020-06-24
scimago Q1
wos Q2
SJR0.717
CiteScore6.7
Impact factor3.4
ISSN18607179, 18607187
Organic Chemistry
Drug Discovery
Biochemistry
Pharmacology
Molecular Medicine
General Pharmacology, Toxicology and Pharmaceutics
Abstract
Luminescent lanthanide fluoride core-shell (LaF3 :Tb3+ ,Ce3+ @SiO2 -NH2 ) nanoparticles, with acetylsalicylic acid (aspirin) coated on the surface have been obtained. The synthesized products, which combine the potential located in the silica shell with the luminescent activity of the core, were characterized in detail with the use of luminescence spectroscopy, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and transmission electron microscopy (TEM) methods. The in vitro effects of the modified luminescent nanoparticles on human red blood cell (RBC) membrane permeability, RBC shape, and sedimentation rate were investigated to assess the hemocompatibility of the obtained compounds. This study demonstrates that LaF3 : Tb3+ 5 %, Ce3+ 10 %@SiO2 -NH2 nanoparticles with acetylsalicylic acid (aspirin) coated on the surface are very good precursors for multifunctional drug-delivery systems or bio-imaging probes that can be used safely in potential biomedical applications.
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Kwiatek D. et al. Surface Modification of Luminescent Ln III Fluoride Core–Shell Nanoparticles with Acetylsalicylic acid (Aspirin): Synthesis, Spectroscopic and in Vitro Hemocompatibility Studies // ChemMedChem. 2020. Vol. 15. No. 15. pp. 1490-1496.
GOST all authors (up to 50) Copy
Kwiatek D., Mrówczyńska L., Stopikowska N., Runowski M., Lesicki A., Lis S. Surface Modification of Luminescent Ln III Fluoride Core–Shell Nanoparticles with Acetylsalicylic acid (Aspirin): Synthesis, Spectroscopic and in Vitro Hemocompatibility Studies // ChemMedChem. 2020. Vol. 15. No. 15. pp. 1490-1496.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1002/cmdc.202000269
UR - https://doi.org/10.1002/cmdc.202000269
TI - Surface Modification of Luminescent Ln III Fluoride Core–Shell Nanoparticles with Acetylsalicylic acid (Aspirin): Synthesis, Spectroscopic and in Vitro Hemocompatibility Studies
T2 - ChemMedChem
AU - Kwiatek, Dorota
AU - Mrówczyńska, Lucyna
AU - Stopikowska, Natalia
AU - Runowski, Marcin
AU - Lesicki, Andrzej
AU - Lis, S.
PY - 2020
DA - 2020/06/24
PB - Wiley
SP - 1490-1496
IS - 15
VL - 15
PMID - 32510839
SN - 1860-7179
SN - 1860-7187
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2020_Kwiatek,
author = {Dorota Kwiatek and Lucyna Mrówczyńska and Natalia Stopikowska and Marcin Runowski and Andrzej Lesicki and S. Lis},
title = {Surface Modification of Luminescent Ln III Fluoride Core–Shell Nanoparticles with Acetylsalicylic acid (Aspirin): Synthesis, Spectroscopic and in Vitro Hemocompatibility Studies},
journal = {ChemMedChem},
year = {2020},
volume = {15},
publisher = {Wiley},
month = {jun},
url = {https://doi.org/10.1002/cmdc.202000269},
number = {15},
pages = {1490--1496},
doi = {10.1002/cmdc.202000269}
}
MLA
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Kwiatek, Dorota, et al. “Surface Modification of Luminescent Ln III Fluoride Core–Shell Nanoparticles with Acetylsalicylic acid (Aspirin): Synthesis, Spectroscopic and in Vitro Hemocompatibility Studies.” ChemMedChem, vol. 15, no. 15, Jun. 2020, pp. 1490-1496. https://doi.org/10.1002/cmdc.202000269.