Rh(III)‐Catalyzed Redox‐Neutral [4+2] Annulation for Direct Assembly of 3‐Acyl Isoquinolin‐1(2 H )‐ones as Potent Antitumor Agents
Publication type: Journal Article
Publication date: 2020-03-01
PubMed ID:
32118370
General Chemistry
Abstract
By virtue of an efficient rhodium(III)-catalyzed redox-neutral C-H activation/ring-opening of a strained ring/[4+2] annulation cascade of N-methoxybenzamides with propargyl cycloalkanols, diverse 3-acyl isoquinolin-1(2H)-ones were directly obtained in good yields and with excellent functional group compatibility. Additionally, their antitumor activities against various human cancer cells including HepG2, A549, MCF-7 and SH-SY5Y were evaluated and the action mechanism of the selected compound was also investigated in vitro. The results revealed that these products possessed a potent efficacy, by inhibiting proliferation and inducing apoptosis in a time-dependent and dose-dependent manner, suggesting that such compounds can serve as promising candidates for anti lung cancer drug discovery.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
European Journal of Organic Chemistry
4 publications, 19.05%
|
|
|
Journal of Organic Chemistry
3 publications, 14.29%
|
|
|
Organic Letters
3 publications, 14.29%
|
|
|
Organic and Biomolecular Chemistry
2 publications, 9.52%
|
|
|
Bulletin of the Chemical Society of Japan
1 publication, 4.76%
|
|
|
Molecular Catalysis
1 publication, 4.76%
|
|
|
Chinese Chemical Letters
1 publication, 4.76%
|
|
|
PLoS ONE
1 publication, 4.76%
|
|
|
Green Chemistry
1 publication, 4.76%
|
|
|
Synthetic Communications
1 publication, 4.76%
|
|
|
ChemCatChem
1 publication, 4.76%
|
|
|
Russian Chemical Reviews
1 publication, 4.76%
|
|
|
Asian Journal of Organic Chemistry
1 publication, 4.76%
|
|
|
1
2
3
4
|
Publishers
|
1
2
3
4
5
6
|
|
|
American Chemical Society (ACS)
6 publications, 28.57%
|
|
|
Wiley
6 publications, 28.57%
|
|
|
Royal Society of Chemistry (RSC)
3 publications, 14.29%
|
|
|
Elsevier
2 publications, 9.52%
|
|
|
Oxford University Press
1 publication, 4.76%
|
|
|
Public Library of Science (PLoS)
1 publication, 4.76%
|
|
|
Taylor & Francis
1 publication, 4.76%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 4.76%
|
|
|
1
2
3
4
5
6
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
21
Total citations:
21
Citations from 2024:
5
(23.81%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Bian M. et al. Rh(III)‐Catalyzed Redox‐Neutral [4+2] Annulation for Direct Assembly of 3‐Acyl Isoquinolin‐1(2 H )‐ones as Potent Antitumor Agents // ChemPlusChem. 2020. Vol. 85. No. 3. pp. 405-410.
GOST all authors (up to 50)
Copy
Bian M., Ma L., Wu M., Wu L., Gao H., Yi W., Zhang C., Zhou Z. Rh(III)‐Catalyzed Redox‐Neutral [4+2] Annulation for Direct Assembly of 3‐Acyl Isoquinolin‐1(2 H )‐ones as Potent Antitumor Agents // ChemPlusChem. 2020. Vol. 85. No. 3. pp. 405-410.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/cplu.201900616
UR - https://doi.org/10.1002/cplu.201900616
TI - Rh(III)‐Catalyzed Redox‐Neutral [4+2] Annulation for Direct Assembly of 3‐Acyl Isoquinolin‐1(2 H )‐ones as Potent Antitumor Agents
T2 - ChemPlusChem
AU - Bian, Mengyao
AU - Ma, Lei
AU - Wu, Min
AU - Wu, Liexin
AU - Gao, Hui
AU - Yi, Wei
AU - Zhang, Chao
AU - Zhou, Zhi
PY - 2020
DA - 2020/03/01
PB - Wiley
SP - 405-410
IS - 3
VL - 85
PMID - 32118370
SN - 2192-6506
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Bian,
author = {Mengyao Bian and Lei Ma and Min Wu and Liexin Wu and Hui Gao and Wei Yi and Chao Zhang and Zhi Zhou},
title = {Rh(III)‐Catalyzed Redox‐Neutral [4+2] Annulation for Direct Assembly of 3‐Acyl Isoquinolin‐1(2 H )‐ones as Potent Antitumor Agents},
journal = {ChemPlusChem},
year = {2020},
volume = {85},
publisher = {Wiley},
month = {mar},
url = {https://doi.org/10.1002/cplu.201900616},
number = {3},
pages = {405--410},
doi = {10.1002/cplu.201900616}
}
Cite this
MLA
Copy
Bian, Mengyao, et al. “Rh(III)‐Catalyzed Redox‐Neutral [4+2] Annulation for Direct Assembly of 3‐Acyl Isoquinolin‐1(2 H )‐ones as Potent Antitumor Agents.” ChemPlusChem, vol. 85, no. 3, Mar. 2020, pp. 405-410. https://doi.org/10.1002/cplu.201900616.