Hybrid molecules based on 1,3,5‐triazine as potential therapeutics: A focused review
Parteek Prasher
1, 2
,
Mousmee Sharma
1, 3
,
Alaa AA Aljabali
4
,
Poonam Negi
5
,
Deepak A. Kapoor
5
,
Inderbir Singh
6
,
Flavia C Zacconi
7
,
Terezinha J A Pinto
8
,
Mateus Webba Da Silva
9
,
Hamid A. Bakshi
9
,
Gaurav Gupta
5, 10, 11, 12
2
Department of Chemistry University of Petroleum & Energy Studies Dehradun India
|
11
Publication type: Journal Article
Publication date: 2020-06-24
scimago Q2
wos Q1
SJR: 0.756
CiteScore: 6.6
Impact factor: 4.2
ISSN: 02724391, 10982299
PubMed ID:
32579723
Drug Discovery
Abstract
Majority of the representative drugs customarily interact with multiple targets manifesting unintended side effects. In addition, drug resistance and over expression of the cellular efflux-pumps render certain classes of drugs ineffective. With only a few innovative formulations in development, it is necessary to identify pharmacophores and novel strategies for creating new drugs. The conjugation of dissimilar pharmacophoric moieties to design hybrid molecules with an attractive therapeutic profile is an emerging paradigm in the contemporary drug development regime. The recent decade witnessed the remarkable biological potential of 1,3,5-triazine framework in the development of various chemotherapeutics. The appending of the 1,3,5-triazine nucleus to biologically relevant moieties has delivered exciting results. The present review focuses on 1,3,5-triazine based hybrid molecules in the development of pharmaceuticals.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
5
|
|
|
Russian Journal of General Chemistry
5 publications, 16.13%
|
|
|
Drug Development Research
2 publications, 6.45%
|
|
|
Organic Letters
2 publications, 6.45%
|
|
|
Russian Journal of Bioorganic Chemistry
2 publications, 6.45%
|
|
|
Journal of Molecular Structure
2 publications, 6.45%
|
|
|
Acta Periodica Technologica
1 publication, 3.23%
|
|
|
Russian Chemical Bulletin
1 publication, 3.23%
|
|
|
Journal of Organometallic Chemistry
1 publication, 3.23%
|
|
|
Molecules
1 publication, 3.23%
|
|
|
Journal of Biochemical and Molecular Toxicology
1 publication, 3.23%
|
|
|
Spectroscopy Letters
1 publication, 3.23%
|
|
|
ChemistrySelect
1 publication, 3.23%
|
|
|
Archiv der Pharmazie
1 publication, 3.23%
|
|
|
ChemChemTech
1 publication, 3.23%
|
|
|
Chemical Engineering Journal
1 publication, 3.23%
|
|
|
Биоорганическая химия
1 publication, 3.23%
|
|
|
Pathology Research and Practice
1 publication, 3.23%
|
|
|
Журнал Общей Химии
1 publication, 3.23%
|
|
|
Mendeleev Communications
1 publication, 3.23%
|
|
|
Journal of Macromolecular Science Part A
1 publication, 3.23%
|
|
|
Dalton Transactions
1 publication, 3.23%
|
|
|
European Journal of Pharmaceutical Sciences
1 publication, 3.23%
|
|
|
1
2
3
4
5
|
Publishers
|
1
2
3
4
5
6
7
8
|
|
|
Pleiades Publishing
8 publications, 25.81%
|
|
|
Elsevier
7 publications, 22.58%
|
|
|
Wiley
5 publications, 16.13%
|
|
|
American Chemical Society (ACS)
2 publications, 6.45%
|
|
|
Taylor & Francis
2 publications, 6.45%
|
|
|
National Library of Serbia
1 publication, 3.23%
|
|
|
Springer Nature
1 publication, 3.23%
|
|
|
MDPI
1 publication, 3.23%
|
|
|
Ivanovo State University of Chemistry and Technology
1 publication, 3.23%
|
|
|
The Russian Academy of Sciences
1 publication, 3.23%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 3.23%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 3.23%
|
|
|
1
2
3
4
5
6
7
8
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
31
Total citations:
31
Citations from 2025:
5
(16.13%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Prasher P. et al. Hybrid molecules based on 1,3,5‐triazine as potential therapeutics: A focused review // Drug Development Research. 2020. Vol. 81. No. 7. pp. 837-858.
GOST all authors (up to 50)
Copy
Prasher P., Sharma M., AA Aljabali A., Negi P., Kapoor D. A., Singh I., Zacconi F. C., A Pinto T. J., Webba Da Silva M., Bakshi H. A., Tambuwala M. M., Gupta G. Hybrid molecules based on 1,3,5‐triazine as potential therapeutics: A focused review // Drug Development Research. 2020. Vol. 81. No. 7. pp. 837-858.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/ddr.21704
UR - https://doi.org/10.1002/ddr.21704
TI - Hybrid molecules based on 1,3,5‐triazine as potential therapeutics: A focused review
T2 - Drug Development Research
AU - Prasher, Parteek
AU - Sharma, Mousmee
AU - AA Aljabali, Alaa
AU - Negi, Poonam
AU - Kapoor, Deepak A.
AU - Singh, Inderbir
AU - Zacconi, Flavia C
AU - A Pinto, Terezinha J
AU - Webba Da Silva, Mateus
AU - Bakshi, Hamid A.
AU - Tambuwala, Murtaza M
AU - Gupta, Gaurav
PY - 2020
DA - 2020/06/24
PB - Wiley
SP - 837-858
IS - 7
VL - 81
PMID - 32579723
SN - 0272-4391
SN - 1098-2299
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Prasher,
author = {Parteek Prasher and Mousmee Sharma and Alaa AA Aljabali and Poonam Negi and Deepak A. Kapoor and Inderbir Singh and Flavia C Zacconi and Terezinha J A Pinto and Mateus Webba Da Silva and Hamid A. Bakshi and Murtaza M Tambuwala and Gaurav Gupta},
title = {Hybrid molecules based on 1,3,5‐triazine as potential therapeutics: A focused review},
journal = {Drug Development Research},
year = {2020},
volume = {81},
publisher = {Wiley},
month = {jun},
url = {https://doi.org/10.1002/ddr.21704},
number = {7},
pages = {837--858},
doi = {10.1002/ddr.21704}
}
Cite this
MLA
Copy
Prasher, Parteek, et al. “Hybrid molecules based on 1,3,5‐triazine as potential therapeutics: A focused review.” Drug Development Research, vol. 81, no. 7, Jun. 2020, pp. 837-858. https://doi.org/10.1002/ddr.21704.