Synthesis of nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides
Тип публикации: Journal Article
Дата публикации: 1974-02-01
scimago Q3
wos Q2
БС2
SJR: 0.362
CiteScore: 4.7
Impact factor: 2.4
ISSN: 0022152X, 19435193
Organic Chemistry
Краткое описание
Nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides were prepared by the acid-catalyzed fusion procedure and by glycosylation of the appropriate trimethylsilyl derivative. The following nucleosides were obtained in two steps starting from methyl 4-substituted-1,2,4-triazole-3-carboxylates: 5-chloro-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (6), 3-chloro-1-β-D-ribofuranosyl-1,2,4-triazole-5-carboxamide (5), 3-nitro-1-β-D-ribofuranosyl-1,2,4-triazole-5-carboxamide (12), 3-amino-1-β-D-ribofuranosyl-1,2,4-triazole-5-carboxamide (13), 5-methyl-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (15), and 3-methyl-1-β-D-ribofuranosyl-1,2,4-triazole-5-carboxamide (16). In addition, 5-amino-1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (7), and 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide-5-thiol (8) were prepared from 6.
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Naik S., Witkowski J. T., Robins R. K. Synthesis of nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides // Journal of Heterocyclic Chemistry. 1974. Vol. 11. No. 1. pp. 57-61.
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Naik S., Witkowski J. T., Robins R. K. Synthesis of nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides // Journal of Heterocyclic Chemistry. 1974. Vol. 11. No. 1. pp. 57-61.
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TY - JOUR
DO - 10.1002/jhet.5570110112
UR - https://doi.org/10.1002/jhet.5570110112
TI - Synthesis of nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides
T2 - Journal of Heterocyclic Chemistry
AU - Naik, S.R.
AU - Witkowski, J. T.
AU - Robins, Roland K.
PY - 1974
DA - 1974/02/01
PB - Wiley
SP - 57-61
IS - 1
VL - 11
SN - 0022-152X
SN - 1943-5193
ER -
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@article{1974_Naik,
author = {S.R. Naik and J. T. Witkowski and Roland K. Robins},
title = {Synthesis of nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides},
journal = {Journal of Heterocyclic Chemistry},
year = {1974},
volume = {11},
publisher = {Wiley},
month = {feb},
url = {https://doi.org/10.1002/jhet.5570110112},
number = {1},
pages = {57--61},
doi = {10.1002/jhet.5570110112}
}
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MLA
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Naik, S.R., et al. “Synthesis of nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides.” Journal of Heterocyclic Chemistry, vol. 11, no. 1, Feb. 1974, pp. 57-61. https://doi.org/10.1002/jhet.5570110112.