New heterocycles from tetrazines and oxadiazoles

The reactivity of 3,4-diamino-1,2,5-oxadiazole () toward nucleophilic substitution of 3,6-bis(3,5-dimethylpyrazol-1yl)-1,2,4,5-tetrazine () was studied. A new class of high nitrogen heterocyclic systems was prepared. It was determined that 3,4-diamino-1,2,5-oxadiazole did not display the required nucleophilicity to be reactive. However, the anion of 3,4-diamino-1,2,5-oxadiazole, prepared by treatment with strong base, was sufficiently reactive to act as a nucleophile. J. Heterocyclic Chem., (2009).