RGD-based PET tracers for imaging receptor integrin αvβ3expression
Тип публикации: Journal Article
Дата публикации: 2013-02-16
scimago Q3
wos Q4
БС2
SJR: 0.271
CiteScore: 2
Impact factor: 0.9
ISSN: 03624803, 10991344
PubMed ID:
24285371
Organic Chemistry
Drug Discovery
Biochemistry
Spectroscopy
Analytical Chemistry
Radiology, Nuclear Medicine and imaging
Краткое описание
Positron emission tomography (PET) imaging of receptor integrin αv β3 expression may play a key role in the early detection of cancer and cardiovascular diseases, monitoring disease progression, evaluating therapeutic response, and aiding anti-angiogenic drugs discovery and development. The last decade has seen the development of new PET tracers for in vivo imaging of integrin αv β3 expression along with advances in PET chemistry. In this review, we will focus on the radiochemistry development of PET tracers based on arginine-glycine-aspartic acid (RGD) peptide, present an overview of general strategies for preparing RGD-based PET tracers, and review the recent advances in preparations of (18) F-labeled, (64) Cu-labeled, and (68) Ga-labeled RGD tracers, RGD-based PET multivalent probes, and RGD-based PET multimodality probes for imaging receptor integrin αv β3 expression.
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Cai H., Conti P. S. RGD-based PET tracers for imaging receptor integrin αvβ3expression // Journal of Labelled Compounds and Radiopharmaceuticals. 2013. Vol. 56. No. 5. pp. 264-279.
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Cai H., Conti P. S. RGD-based PET tracers for imaging receptor integrin αvβ3expression // Journal of Labelled Compounds and Radiopharmaceuticals. 2013. Vol. 56. No. 5. pp. 264-279.
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TY - JOUR
DO - 10.1002/jlcr.2999
UR - https://doi.org/10.1002/jlcr.2999
TI - RGD-based PET tracers for imaging receptor integrin αvβ3expression
T2 - Journal of Labelled Compounds and Radiopharmaceuticals
AU - Cai, Hancheng
AU - Conti, Peter S.
PY - 2013
DA - 2013/02/16
PB - Wiley
SP - 264-279
IS - 5
VL - 56
PMID - 24285371
SN - 0362-4803
SN - 1099-1344
ER -
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@article{2013_Cai,
author = {Hancheng Cai and Peter S. Conti},
title = {RGD-based PET tracers for imaging receptor integrin αvβ3expression},
journal = {Journal of Labelled Compounds and Radiopharmaceuticals},
year = {2013},
volume = {56},
publisher = {Wiley},
month = {feb},
url = {https://doi.org/10.1002/jlcr.2999},
number = {5},
pages = {264--279},
doi = {10.1002/jlcr.2999}
}
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MLA
Скопировать
Cai, Hancheng, et al. “RGD-based PET tracers for imaging receptor integrin αvβ3expression.” Journal of Labelled Compounds and Radiopharmaceuticals, vol. 56, no. 5, Feb. 2013, pp. 264-279. https://doi.org/10.1002/jlcr.2999.