An Easy Synthetic Access to Spiro Derivatives Containing Pyrido[1,2-a]pyrimidine and Quinoline Scaffolds and Their Antimicrobial Activity.
Тип публикации: Journal Article
Дата публикации: 2017-05-15
General Chemistry
Краткое описание
A series of novel spiro derivatives containing pyrido[1,2-a]pyrimidine and quinoline moieties was designed and synthesized, and their structures were characterized by 1H, 13C NMR, IR, Mass Spectral and elemental analysis. This protocol has the advantages of good yields, broad substrate scope and simple work-up. Their antimicrobial activity against a panel of various bacterial strains and unicellular and multicellular pathogenic fungal strains were evaluated, and the result indicated that some of the title compounds showed excellent activities against reference drugs. The spiro compounds with different substituents, namely 6 a, 6 c and 7 e displayed promising in vitro antimicrobial activity.
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Verma A. K. et al. An Easy Synthetic Access to Spiro Derivatives Containing Pyrido[1,2-a]pyrimidine and Quinoline Scaffolds and Their Antimicrobial Activity. // ChemistrySelect. 2017. Vol. 2. No. 14. pp. 4006-4009.
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Verma A. K., Bishnoi A., Fatma S., Parveen H., Singh V. An Easy Synthetic Access to Spiro Derivatives Containing Pyrido[1,2-a]pyrimidine and Quinoline Scaffolds and Their Antimicrobial Activity. // ChemistrySelect. 2017. Vol. 2. No. 14. pp. 4006-4009.
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TY - JOUR
DO - 10.1002/slct.201700228
UR - https://doi.org/10.1002/slct.201700228
TI - An Easy Synthetic Access to Spiro Derivatives Containing Pyrido[1,2-a]pyrimidine and Quinoline Scaffolds and Their Antimicrobial Activity.
T2 - ChemistrySelect
AU - Verma, Anil Kumar
AU - Bishnoi, Abha
AU - Fatma, Shaheen
AU - Parveen, Huda
AU - Singh, Vineeta
PY - 2017
DA - 2017/05/15
PB - Wiley
SP - 4006-4009
IS - 14
VL - 2
SN - 2365-6549
ER -
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@article{2017_Verma,
author = {Anil Kumar Verma and Abha Bishnoi and Shaheen Fatma and Huda Parveen and Vineeta Singh},
title = {An Easy Synthetic Access to Spiro Derivatives Containing Pyrido[1,2-a]pyrimidine and Quinoline Scaffolds and Their Antimicrobial Activity.},
journal = {ChemistrySelect},
year = {2017},
volume = {2},
publisher = {Wiley},
month = {may},
url = {https://doi.org/10.1002/slct.201700228},
number = {14},
pages = {4006--4009},
doi = {10.1002/slct.201700228}
}
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Verma, Anil Kumar, et al. “An Easy Synthetic Access to Spiro Derivatives Containing Pyrido[1,2-a]pyrimidine and Quinoline Scaffolds and Their Antimicrobial Activity..” ChemistrySelect, vol. 2, no. 14, May. 2017, pp. 4006-4009. https://doi.org/10.1002/slct.201700228.