Selective Inhibition of Enterovirus A Species Members’ Reproduction by Furano[2, 3-d ]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses
Liubov I. Kozlovskaya
1, 2
,
Anastasia D Golinets
1, 2
,
Anastasia A Eletskaya
1, 3
,
Alexey A. Orlov
1, 3
,
V. A. Palyulin
3
,
С. Н. Кочетков
4
,
Liudmila A Alexandrova
4
,
Dmitry I. Osolodkin
1, 2, 3
Publication type: Journal Article
Publication date: 2018-02-27
PubMed ID:
32328513
General Chemistry
Abstract
Abstract The rational design of broad‐spectrum antivirals requires data on antiviral activity of compounds against multiple viruses, which are often not available. We have developed a panel of (+)ssRNA viruses composed of Enterovirus and Flavivirus genera members allowing to study these activity spectra. Antiviral activity profiling of a set of nucleoside analogues revealed N 4‐hydroxycytidine as an efficient inhibitor of replication of coxsackieviruses and other enteroviruses, but ineffective against tick‐borne encephalitis virus. Furano[2, 3‐d]pyrimidine nucleosides with n‐pentyl or n‐hexyl tails showed selective inhibition of Enterovirus A representatives. 5‐(Tetradec‐1‐yn‐1‐yl)‐uridine showed selective inhibition of tick‐borne encephalitis virus at the micromolar level.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
|
|
|
European Journal of Medicinal Chemistry
3 publications, 12%
|
|
|
Antiviral Research
2 publications, 8%
|
|
|
Annual Reports in Medicinal Chemistry
2 publications, 8%
|
|
|
Journal of Antibiotics
1 publication, 4%
|
|
|
Antiviral Chemistry and Chemotherapy
1 publication, 4%
|
|
|
Scientific Reports
1 publication, 4%
|
|
|
Toxicology in Vitro
1 publication, 4%
|
|
|
Tetrahedron Letters
1 publication, 4%
|
|
|
Archiv der Pharmazie
1 publication, 4%
|
|
|
Molecular Informatics
1 publication, 4%
|
|
|
Journal of Agricultural and Food Chemistry
1 publication, 4%
|
|
|
RSC Advances
1 publication, 4%
|
|
|
ChemistrySelect
1 publication, 4%
|
|
|
Mini-Reviews in Medicinal Chemistry
1 publication, 4%
|
|
|
Bioorganic and Medicinal Chemistry
1 publication, 4%
|
|
|
Microbiology spectrum
1 publication, 4%
|
|
|
Heliyon
1 publication, 4%
|
|
|
Chemical Biology and Drug Design
1 publication, 4%
|
|
|
Applied Organometallic Chemistry
1 publication, 4%
|
|
|
ACS Infectious Diseases
1 publication, 4%
|
|
|
New Journal of Chemistry
1 publication, 4%
|
|
|
1
2
3
|
Publishers
|
2
4
6
8
10
12
|
|
|
Elsevier
11 publications, 44%
|
|
|
Wiley
5 publications, 20%
|
|
|
Springer Nature
2 publications, 8%
|
|
|
American Chemical Society (ACS)
2 publications, 8%
|
|
|
Royal Society of Chemistry (RSC)
2 publications, 8%
|
|
|
SAGE
1 publication, 4%
|
|
|
Bentham Science Publishers Ltd.
1 publication, 4%
|
|
|
American Society for Microbiology
1 publication, 4%
|
|
|
2
4
6
8
10
12
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
25
Total citations:
25
Citations from 2024:
7
(28%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Kozlovskaya L. I. et al. Selective Inhibition of Enterovirus A Species Members’ Reproduction by Furano[2, 3-d ]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses // ChemistrySelect. 2018. Vol. 3. No. 8. pp. 2321-2325.
GOST all authors (up to 50)
Copy
Kozlovskaya L. I., Golinets A. D., Eletskaya A. A., Orlov A. A., Palyulin V. A., Кочетков С. Н., Alexandrova L. A., Osolodkin D. I. Selective Inhibition of Enterovirus A Species Members’ Reproduction by Furano[2, 3-d ]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses // ChemistrySelect. 2018. Vol. 3. No. 8. pp. 2321-2325.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/slct.201703052
UR - https://doi.org/10.1002/slct.201703052
TI - Selective Inhibition of Enterovirus A Species Members’ Reproduction by Furano[2, 3-d ]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses
T2 - ChemistrySelect
AU - Kozlovskaya, Liubov I.
AU - Golinets, Anastasia D
AU - Eletskaya, Anastasia A
AU - Orlov, Alexey A.
AU - Palyulin, V. A.
AU - Кочетков, С. Н.
AU - Alexandrova, Liudmila A
AU - Osolodkin, Dmitry I.
PY - 2018
DA - 2018/02/27
PB - Wiley
SP - 2321-2325
IS - 8
VL - 3
PMID - 32328513
SN - 2365-6549
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_Kozlovskaya,
author = {Liubov I. Kozlovskaya and Anastasia D Golinets and Anastasia A Eletskaya and Alexey A. Orlov and V. A. Palyulin and С. Н. Кочетков and Liudmila A Alexandrova and Dmitry I. Osolodkin},
title = {Selective Inhibition of Enterovirus A Species Members’ Reproduction by Furano[2, 3-d ]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses},
journal = {ChemistrySelect},
year = {2018},
volume = {3},
publisher = {Wiley},
month = {feb},
url = {https://doi.org/10.1002/slct.201703052},
number = {8},
pages = {2321--2325},
doi = {10.1002/slct.201703052}
}
Cite this
MLA
Copy
Kozlovskaya, Liubov I., et al. “Selective Inhibition of Enterovirus A Species Members’ Reproduction by Furano[2, 3-d ]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses.” ChemistrySelect, vol. 3, no. 8, Feb. 2018, pp. 2321-2325. https://doi.org/10.1002/slct.201703052.