ChemistrySelect, volume 4, issue 37, pages 11038-11042
Reactions of 1-(3,3-Diethoxypropyl)urea with Phenols: Synthesis of 1,6-Disubstituted Tetrahydropyrimidine-2(1H)-ones
Publication type: Journal Article
Publication date: 2019-10-02
Journal:
ChemistrySelect
Quartile SCImago
Q2
Quartile WOS
Q3
Impact factor: 2.1
ISSN: 23656549, 23656549
General Chemistry
Abstract
Ureas containing alkyl aromatic fragments are an important class of organic compounds due to their high pharmacological activity. However, at the moment there is no common and simple method for the synthesis of these classes of compounds. Therefore, in the present work we propose a new approach to the synthesis of 1,6‐disubstituted tetrahydropyrimidine‐2(1H)‐ones via the acid‐catalyzed reaction of (3,3‐diethoxypropyl) urea with various phenols. The proposed approach allows to obtain target compounds in one‐pot manner and without the use of expensive reagents and catalysts.
Top-30
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Tetrahedron
1 publication, 50%
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Russian Journal of General Chemistry
1 publication, 50%
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Elsevier
1 publication, 50%
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Pleiades Publishing
1 publication, 50%
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Smolobochkin A. V. et al. Reactions of 1-(3,3-Diethoxypropyl)urea with Phenols: Synthesis of 1,6-Disubstituted Tetrahydropyrimidine-2(1H)-ones // ChemistrySelect. 2019. Vol. 4. No. 37. pp. 11038-11042.
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Smolobochkin A. V., Gazizov A. S., Voronina J. K., Strelnik A. G., Rizbayeva T. S., Burilov A. R., Pudovik M. A. Reactions of 1-(3,3-Diethoxypropyl)urea with Phenols: Synthesis of 1,6-Disubstituted Tetrahydropyrimidine-2(1H)-ones // ChemistrySelect. 2019. Vol. 4. No. 37. pp. 11038-11042.
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TY - JOUR
DO - 10.1002/slct.201902754
UR - https://doi.org/10.1002/slct.201902754
TI - Reactions of 1-(3,3-Diethoxypropyl)urea with Phenols: Synthesis of 1,6-Disubstituted Tetrahydropyrimidine-2(1H)-ones
T2 - ChemistrySelect
AU - Strelnik, Anna G
AU - Rizbayeva, Tanzilya S
AU - Pudovik, Michail A.
AU - Smolobochkin, Andrey V.
AU - Gazizov, Almir S.
AU - Voronina, Julia K.
AU - Burilov, Alexander R.
PY - 2019
DA - 2019/10/02 00:00:00
PB - Wiley
SP - 11038-11042
IS - 37
VL - 4
SN - 2365-6549
SN - 2365-6549
ER -
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@article{2019_Smolobochkin,
author = {Anna G Strelnik and Tanzilya S Rizbayeva and Michail A. Pudovik and Andrey V. Smolobochkin and Almir S. Gazizov and Julia K. Voronina and Alexander R. Burilov},
title = {Reactions of 1-(3,3-Diethoxypropyl)urea with Phenols: Synthesis of 1,6-Disubstituted Tetrahydropyrimidine-2(1H)-ones},
journal = {ChemistrySelect},
year = {2019},
volume = {4},
publisher = {Wiley},
month = {oct},
url = {https://doi.org/10.1002/slct.201902754},
number = {37},
pages = {11038--11042},
doi = {10.1002/slct.201902754}
}
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Smolobochkin, Andrey V., et al. “Reactions of 1-(3,3-Diethoxypropyl)urea with Phenols: Synthesis of 1,6-Disubstituted Tetrahydropyrimidine-2(1H)-ones.” ChemistrySelect, vol. 4, no. 37, Oct. 2019, pp. 11038-11042. https://doi.org/10.1002/slct.201902754.