Acid‐Catalyzed Tandem Ritter and Mannich Reactions for Direct Access to 3‐Aryl 3‐amidooxindoles from Isatin
2
Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 INDIA
|
Publication type: Journal Article
Publication date: 2023-12-15
General Chemistry
Abstract
Three‐component tandem Ritter and Mannich reactions were developed for one‐pot arylation and acyl protected amination of isatin. The acid catalyzed reaction produced wide variety of 3‐aryl‐3‐amidooxindoles directly from commercially available isatin. The C3 functionalization of isatin is affected by condensation with electron rich arenes and nitriles or amides with concomitant C−C and C−N bonds formation. Substituted isatins, different nucleophiles (cyclic and acyclic N, N‐disubstituted arylamines), aliphatic nitriles, and amides expanded the scope of the reaction. The reaction is simple, general, efficient and can switch the amidation substrate from nitriles in Ritter reaction to amides in Mannich reaction.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
|
|
|
ChemistrySelect
1 publication, 33.33%
|
|
|
Journal of Molecular Structure
1 publication, 33.33%
|
|
|
Russian Chemical Reviews
1 publication, 33.33%
|
|
|
1
|
Publishers
|
1
|
|
|
Wiley
1 publication, 33.33%
|
|
|
Elsevier
1 publication, 33.33%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 33.33%
|
|
|
1
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
3
Total citations:
3
Citations from 2024:
3
(100%)
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Sudheer Kumar K. et al. Acid‐Catalyzed Tandem Ritter and Mannich Reactions for Direct Access to 3‐Aryl 3‐amidooxindoles from Isatin // ChemistrySelect. 2023. Vol. 8. No. 47.
GOST all authors (up to 50)
Copy
Sudheer Kumar K., Pilli N., Chandrasekharam M. Acid‐Catalyzed Tandem Ritter and Mannich Reactions for Direct Access to 3‐Aryl 3‐amidooxindoles from Isatin // ChemistrySelect. 2023. Vol. 8. No. 47.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1002/slct.202304188
UR - https://doi.org/10.1002/slct.202304188
TI - Acid‐Catalyzed Tandem Ritter and Mannich Reactions for Direct Access to 3‐Aryl 3‐amidooxindoles from Isatin
T2 - ChemistrySelect
AU - Sudheer Kumar, Karu
AU - Pilli, Navyasree
AU - Chandrasekharam, M.
PY - 2023
DA - 2023/12/15
PB - Wiley
IS - 47
VL - 8
SN - 2365-6549
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_Sudheer Kumar,
author = {Karu Sudheer Kumar and Navyasree Pilli and M. Chandrasekharam},
title = {Acid‐Catalyzed Tandem Ritter and Mannich Reactions for Direct Access to 3‐Aryl 3‐amidooxindoles from Isatin},
journal = {ChemistrySelect},
year = {2023},
volume = {8},
publisher = {Wiley},
month = {dec},
url = {https://doi.org/10.1002/slct.202304188},
number = {47},
doi = {10.1002/slct.202304188}
}