Substituted 3-oxo-1,2,5-Thiadiazolidine 1,1-Dioxides: A New Class of Potential Mechanism-Based Inhibitors of Human Leukocyte Elastase and Cathepsin G
Publication type: Journal Article
Publication date: 1994-01-01
scimago Q2
wos Q3
SJR: 0.748
CiteScore: 4.9
Impact factor: 2.2
ISSN: 0006291X, 10902104
PubMed ID:
8292039
Biochemistry
Molecular Biology
Cell Biology
Biophysics
Abstract
A series of substituted 3-oxo-1,2,5-thiadiazolidine 1,1-dioxides has been synthesized and their in vitro inhibitory activity toward human leukocyte elastase and cathepsin G was investigated. These compounds were found to inactivate the two enzymes efficiently and in a time-dependent fashion.
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Groutas W. C., Kuang R., Venkataraman R. Substituted 3-oxo-1,2,5-Thiadiazolidine 1,1-Dioxides: A New Class of Potential Mechanism-Based Inhibitors of Human Leukocyte Elastase and Cathepsin G // Biochemical and Biophysical Research Communications. 1994. Vol. 198. No. 1. pp. 341-349.
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Groutas W. C., Kuang R., Venkataraman R. Substituted 3-oxo-1,2,5-Thiadiazolidine 1,1-Dioxides: A New Class of Potential Mechanism-Based Inhibitors of Human Leukocyte Elastase and Cathepsin G // Biochemical and Biophysical Research Communications. 1994. Vol. 198. No. 1. pp. 341-349.
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RIS
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TY - JOUR
DO - 10.1006/bbrc.1994.1048
UR - https://doi.org/10.1006/bbrc.1994.1048
TI - Substituted 3-oxo-1,2,5-Thiadiazolidine 1,1-Dioxides: A New Class of Potential Mechanism-Based Inhibitors of Human Leukocyte Elastase and Cathepsin G
T2 - Biochemical and Biophysical Research Communications
AU - Groutas, William C.
AU - Kuang, R.Z.
AU - Venkataraman, R.
PY - 1994
DA - 1994/01/01
PB - Elsevier
SP - 341-349
IS - 1
VL - 198
PMID - 8292039
SN - 0006-291X
SN - 1090-2104
ER -
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BibTex (up to 50 authors)
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@article{1994_Groutas,
author = {William C. Groutas and R.Z. Kuang and R. Venkataraman},
title = {Substituted 3-oxo-1,2,5-Thiadiazolidine 1,1-Dioxides: A New Class of Potential Mechanism-Based Inhibitors of Human Leukocyte Elastase and Cathepsin G},
journal = {Biochemical and Biophysical Research Communications},
year = {1994},
volume = {198},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1006/bbrc.1994.1048},
number = {1},
pages = {341--349},
doi = {10.1006/bbrc.1994.1048}
}
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MLA
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Groutas, William C., et al. “Substituted 3-oxo-1,2,5-Thiadiazolidine 1,1-Dioxides: A New Class of Potential Mechanism-Based Inhibitors of Human Leukocyte Elastase and Cathepsin G.” Biochemical and Biophysical Research Communications, vol. 198, no. 1, Jan. 1994, pp. 341-349. https://doi.org/10.1006/bbrc.1994.1048.