A Two-Stage Lightweight Deep Learning Framework for Mass Detection and Segmentation in Mammograms Using YOLOv5 and Depthwise SegNet

Publication typeJournal Article
Publication date2025-03-14
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ISSN29482933, 29482925
Abstract

Ensuring strict medical data privacy standards while delivering efficient and accurate breast cancer segmentation is a critical challenge. This paper addresses this challenge by proposing a lightweight solution capable of running directly in the user’s browser, ensuring that medical data never leave the user’s computer. Our proposed solution consists of a two-stage model: the pre-trained nano YoloV5 variation handles the task of mass detection, while a lightweight neural network model of just 20k parameters and an inference time of 21 ms per image addresses the segmentation problem. This highly efficient model in terms of inference speed and memory consumption was created by combining well-known techniques, such as the SegNet architecture and depthwise separable convolutions. The detection model manages an mAP@50 equal to 50.3% on the CBIS-DDSM dataset and 68.2% on the INbreast dataset. Despite its size, our segmentation model produces high-performance levels on the CBIS-DDSM (81.0% IoU, 89.4% Dice) and INbreast (77.3% IoU, 87.0% Dice) dataset.

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Manolakis D. et al. A Two-Stage Lightweight Deep Learning Framework for Mass Detection and Segmentation in Mammograms Using YOLOv5 and Depthwise SegNet // Journal of Imaging Informatics in Medicine. 2025.
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Manolakis D., Bizopoulos P., Lalas A., Konstantinos V. A Two-Stage Lightweight Deep Learning Framework for Mass Detection and Segmentation in Mammograms Using YOLOv5 and Depthwise SegNet // Journal of Imaging Informatics in Medicine. 2025.
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TY - JOUR
DO - 10.1007/s10278-025-01471-0
UR - https://link.springer.com/10.1007/s10278-025-01471-0
TI - A Two-Stage Lightweight Deep Learning Framework for Mass Detection and Segmentation in Mammograms Using YOLOv5 and Depthwise SegNet
T2 - Journal of Imaging Informatics in Medicine
AU - Manolakis, Dimitris
AU - Bizopoulos, Paschalis
AU - Lalas, Antonios
AU - Konstantinos, Votis
PY - 2025
DA - 2025/03/14
PB - Springer Nature
SN - 2948-2933
SN - 2948-2925
ER -
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@article{2025_Manolakis,
author = {Dimitris Manolakis and Paschalis Bizopoulos and Antonios Lalas and Votis Konstantinos},
title = {A Two-Stage Lightweight Deep Learning Framework for Mass Detection and Segmentation in Mammograms Using YOLOv5 and Depthwise SegNet},
journal = {Journal of Imaging Informatics in Medicine},
year = {2025},
publisher = {Springer Nature},
month = {mar},
url = {https://link.springer.com/10.1007/s10278-025-01471-0},
doi = {10.1007/s10278-025-01471-0}
}