Production of a Short-Lived Therapeutic α-Emitter 149Tb by Irradiation of Europium by 63 MeV α-Particles
R. A. Aliev
1
,
V A Zagryadskiy
1
,
S T Latushkin
1
,
A N Moiseeva
1
,
V.I. Novikov
1
,
V N Unezhev
1
,
Publication type: Journal Article
Publication date: 2021-04-01
scimago Q3
wos Q4
SJR: 0.285
CiteScore: 0.7
Impact factor: 0.3
ISSN: 10634258, 15738205
Nuclear Energy and Engineering
Abstract
149Tb is currently considered to be a promising α-emitting isotope radioimmunotherapy. It is shown that it can be obtained without the use of a carrier by irradiating a target consisting of Eu2O3 with 4He with energy 63 MeV. After irradiation, radiochemical separation of terbium radioisotopes was performed in a time not exceeding the half-life of 149Tb (4.12 h). It was based on reductive co-precipitation of europium and extraction-chromatographic purification. The obtained product, including 149Tb and the associated terbium radioisotopes, were analyzed by means of alpha- and gamma-spectrometry. It was concluded that the combination and sequence of approaches used in this work allow rapid production of short-lived 149Tb and the use of the technological route implemented in this work in practice.
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GOST
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Aliev R. A. et al. Production of a Short-Lived Therapeutic α-Emitter 149Tb by Irradiation of Europium by 63 MeV α-Particles // Atomic Energy. 2021. Vol. 129. No. 6. pp. 337-340.
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Aliev R. A., Zagryadskiy V. A., Latushkin S. T., Moiseeva A. N., Novikov V., Unezhev V. N., Kazakov A. G. Production of a Short-Lived Therapeutic α-Emitter 149Tb by Irradiation of Europium by 63 MeV α-Particles // Atomic Energy. 2021. Vol. 129. No. 6. pp. 337-340.
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RIS
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TY - JOUR
DO - 10.1007/s10512-021-00758-z
UR - https://doi.org/10.1007/s10512-021-00758-z
TI - Production of a Short-Lived Therapeutic α-Emitter 149Tb by Irradiation of Europium by 63 MeV α-Particles
T2 - Atomic Energy
AU - Aliev, R. A.
AU - Zagryadskiy, V A
AU - Latushkin, S T
AU - Moiseeva, A N
AU - Novikov, V.I.
AU - Unezhev, V N
AU - Kazakov, A G
PY - 2021
DA - 2021/04/01
PB - Springer Nature
SP - 337-340
IS - 6
VL - 129
SN - 1063-4258
SN - 1573-8205
ER -
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BibTex (up to 50 authors)
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@article{2021_Aliev,
author = {R. A. Aliev and V A Zagryadskiy and S T Latushkin and A N Moiseeva and V.I. Novikov and V N Unezhev and A G Kazakov},
title = {Production of a Short-Lived Therapeutic α-Emitter 149Tb by Irradiation of Europium by 63 MeV α-Particles},
journal = {Atomic Energy},
year = {2021},
volume = {129},
publisher = {Springer Nature},
month = {apr},
url = {https://doi.org/10.1007/s10512-021-00758-z},
number = {6},
pages = {337--340},
doi = {10.1007/s10512-021-00758-z}
}
Cite this
MLA
Copy
Aliev, R. A., et al. “Production of a Short-Lived Therapeutic α-Emitter 149Tb by Irradiation of Europium by 63 MeV α-Particles.” Atomic Energy, vol. 129, no. 6, Apr. 2021, pp. 337-340. https://doi.org/10.1007/s10512-021-00758-z.
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