Involvement of Receptor Apparatus in the Realization of Antinociceptive Activity of Songorine
Yu V Nesterova
1
,
A V Mukhomedzyanov
2
,
T N Povetyeva
1
,
N I Suslov
1
,
P V Kulpin
1
,
O G Afanaseva
1
,
A V Vychuzhanina
1
,
O Yu Rybalkina
1
,
G N Zyuzkov
1
,
V. V. Zhdanov
1
,
M Yu Minakova
1
Publication type: Journal Article
Publication date: 2025-02-01
scimago Q3
wos Q4
SJR: 0.277
CiteScore: 1.5
Impact factor: 0.6
ISSN: 00074888, 15738221, 03659615, 24131008
Abstract
The receptor mechanism of the antinociceptive effect of the diterpene alkaloid songorine was investigated in an experiment on mice. Antagonists of peripheral opioid, κ-opioid, and cannabinoid 1 receptors eliminated the analgesic effect of songorine. These findings suggest that these receptors are involved in the antinociceptive action of songorine.
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Nesterova Yu. V. et al. Involvement of Receptor Apparatus in the Realization of Antinociceptive Activity of Songorine // Bulletin of Experimental Biology and Medicine. 2025. Vol. 178. No. 4. pp. 423-426.
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Nesterova Yu. V., Mukhomedzyanov A. V., Povetyeva T. N., Suslov N. I., Kulpin P. V., Afanaseva O. G., Vychuzhanina A. V., Rybalkina O. Yu., Zyuzkov G. N., Zhdanov V. V., Minakova M. Yu. Involvement of Receptor Apparatus in the Realization of Antinociceptive Activity of Songorine // Bulletin of Experimental Biology and Medicine. 2025. Vol. 178. No. 4. pp. 423-426.
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TY - JOUR
DO - 10.1007/s10517-025-06349-3
UR - https://link.springer.com/10.1007/s10517-025-06349-3
TI - Involvement of Receptor Apparatus in the Realization of Antinociceptive Activity of Songorine
T2 - Bulletin of Experimental Biology and Medicine
AU - Nesterova, Yu V
AU - Mukhomedzyanov, A V
AU - Povetyeva, T N
AU - Suslov, N I
AU - Kulpin, P V
AU - Afanaseva, O G
AU - Vychuzhanina, A V
AU - Rybalkina, O Yu
AU - Zyuzkov, G N
AU - Zhdanov, V. V.
AU - Minakova, M Yu
PY - 2025
DA - 2025/02/01
PB - Springer Nature
SP - 423-426
IS - 4
VL - 178
SN - 0007-4888
SN - 1573-8221
SN - 0365-9615
SN - 2413-1008
ER -
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@article{2025_Nesterova,
author = {Yu V Nesterova and A V Mukhomedzyanov and T N Povetyeva and N I Suslov and P V Kulpin and O G Afanaseva and A V Vychuzhanina and O Yu Rybalkina and G N Zyuzkov and V. V. Zhdanov and M Yu Minakova},
title = {Involvement of Receptor Apparatus in the Realization of Antinociceptive Activity of Songorine},
journal = {Bulletin of Experimental Biology and Medicine},
year = {2025},
volume = {178},
publisher = {Springer Nature},
month = {feb},
url = {https://link.springer.com/10.1007/s10517-025-06349-3},
number = {4},
pages = {423--426},
doi = {10.1007/s10517-025-06349-3}
}
Cite this
MLA
Copy
Nesterova, Yu. V., et al. “Involvement of Receptor Apparatus in the Realization of Antinociceptive Activity of Songorine.” Bulletin of Experimental Biology and Medicine, vol. 178, no. 4, Feb. 2025, pp. 423-426. https://link.springer.com/10.1007/s10517-025-06349-3.