Chemistry of Heterocyclic Compounds, volume 43, issue 4, pages 485-489

Synthesis and properties of (6-methyl-2-oxo-4-thioxo-1,2,3,4-tetrahydro-3-pyrimidinyl)acetic acid methyl ester

Publication type: Journal Article
Publication date: 2007-04-01
scimago Q4
wos Q3
SJR: 0.246
CiteScore: 2.9
Impact factor: 1.4
ISSN: 00093122, 15738353
Organic Chemistry
Abstract
On interacting of the methyl ester of (6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-3-pyrimidinyl)acetic acid with the Lawesson’s reagent the corresponding 4-thioxo derivative is synthesized. Its alkylation with methyl bromoacetate has been studied as has its interaction with N-nucleophiles, amines, and hydrazines.
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