Synthesis and Antiinflammatory and Analgesic Activity of 2H-3,3-Dimethyl-3,4-dihydroisoquinolin-1-ones
Publication type: Journal Article
Publication date: 2005-08-01
scimago Q4
wos Q4
SJR: 0.219
CiteScore: 1.4
Impact factor: 1.0
ISSN: 0091150X, 15739031
Drug Discovery
Pharmacology
Abstract
The reactions of substituted arenes with isobutyric aldehyde and methylthiocyanate yield 1-methylthio-3,4-dihydroisoquinolines. The subsequent treatment with AcOH/AcONa yields 2H-3,3-dimethyl-3,4-dihydroisoquinolin-1-ones, some of which exhibit pronounced antiinflammatory and analgesic properties.
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16
Total citations:
16
Citations from 2024:
1
(6.25%)
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GOST
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Vikharev Yu. B. et al. Synthesis and Antiinflammatory and Analgesic Activity of 2H-3,3-Dimethyl-3,4-dihydroisoquinolin-1-ones // Pharmaceutical Chemistry Journal. 2005. Vol. 39. No. 8. pp. 405-408.
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Vikharev Yu. B., Shklyaev Yu. V., Anikina L. V., Kolla V. E., Tolstikov A. Synthesis and Antiinflammatory and Analgesic Activity of 2H-3,3-Dimethyl-3,4-dihydroisoquinolin-1-ones // Pharmaceutical Chemistry Journal. 2005. Vol. 39. No. 8. pp. 405-408.
Cite this
RIS
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TY - JOUR
DO - 10.1007/s11094-005-0168-y
UR - https://doi.org/10.1007/s11094-005-0168-y
TI - Synthesis and Antiinflammatory and Analgesic Activity of 2H-3,3-Dimethyl-3,4-dihydroisoquinolin-1-ones
T2 - Pharmaceutical Chemistry Journal
AU - Vikharev, Yu B
AU - Shklyaev, Yu V
AU - Anikina, L V
AU - Kolla, V E
AU - Tolstikov, A.G
PY - 2005
DA - 2005/08/01
PB - Springer Nature
SP - 405-408
IS - 8
VL - 39
SN - 0091-150X
SN - 1573-9031
ER -
Cite this
BibTex (up to 50 authors)
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@article{2005_Vikharev,
author = {Yu B Vikharev and Yu V Shklyaev and L V Anikina and V E Kolla and A.G Tolstikov},
title = {Synthesis and Antiinflammatory and Analgesic Activity of 2H-3,3-Dimethyl-3,4-dihydroisoquinolin-1-ones},
journal = {Pharmaceutical Chemistry Journal},
year = {2005},
volume = {39},
publisher = {Springer Nature},
month = {aug},
url = {https://doi.org/10.1007/s11094-005-0168-y},
number = {8},
pages = {405--408},
doi = {10.1007/s11094-005-0168-y}
}
Cite this
MLA
Copy
Vikharev, Yu. B., et al. “Synthesis and Antiinflammatory and Analgesic Activity of 2H-3,3-Dimethyl-3,4-dihydroisoquinolin-1-ones.” Pharmaceutical Chemistry Journal, vol. 39, no. 8, Aug. 2005, pp. 405-408. https://doi.org/10.1007/s11094-005-0168-y.