Springer Nature
Pharmaceutical Chemistry Journal
,  volume 47 ,  issue 4 ,  pages 217-218

Improved Synthesis of 2-(1-Adamantyl)-4-bromophenol and 2-(1-Adamantyl)-4-bromoanisole, Intermediates in Adapalene Synthesis

Publication type: Journal Article
Publication date: 2013-07-01
Springer Nature
scimago Q4
wos Q4
SJR: 0.219
CiteScore: 1.4
Impact factor: 1.0
ISSN: 0091150X, 15739031
Drug Discovery
Pharmacology
Abstract
A new simple and environmentally friendly synthetic method for 2-(1-adamantyl)-4-bromophenol that did not use catalysts and solvents was developed. A new simplified preparation method for 2-(1-adamantyl)-4-bromoanisole in one step instead of two was proposed. Both compounds are intermediates in the first and second synthetic steps to 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid (adapalene).
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Sokolenko V. A. et al. Improved Synthesis of 2-(1-Adamantyl)-4-bromophenol and 2-(1-Adamantyl)-4-bromoanisole, Intermediates in Adapalene Synthesis // Pharmaceutical Chemistry Journal. 2013. Vol. 47. No. 4. pp. 217-218.
GOST all authors (up to 50) Copy
Sokolenko V. A., Svirskaya N. M., Peterson I. V., Rubailo A. I. Improved Synthesis of 2-(1-Adamantyl)-4-bromophenol and 2-(1-Adamantyl)-4-bromoanisole, Intermediates in Adapalene Synthesis // Pharmaceutical Chemistry Journal. 2013. Vol. 47. No. 4. pp. 217-218.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1007/s11094-013-0931-4
UR - https://doi.org/10.1007/s11094-013-0931-4
TI - Improved Synthesis of 2-(1-Adamantyl)-4-bromophenol and 2-(1-Adamantyl)-4-bromoanisole, Intermediates in Adapalene Synthesis
T2 - Pharmaceutical Chemistry Journal
AU - Sokolenko, V A
AU - Svirskaya, N M
AU - Peterson, I V
AU - Rubailo, A I
PY - 2013
DA - 2013/07/01
PB - Springer Nature
SP - 217-218
IS - 4
VL - 47
SN - 0091-150X
SN - 1573-9031
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2013_Sokolenko,
author = {V A Sokolenko and N M Svirskaya and I V Peterson and A I Rubailo},
title = {Improved Synthesis of 2-(1-Adamantyl)-4-bromophenol and 2-(1-Adamantyl)-4-bromoanisole, Intermediates in Adapalene Synthesis},
journal = {Pharmaceutical Chemistry Journal},
year = {2013},
volume = {47},
publisher = {Springer Nature},
month = {jul},
url = {https://doi.org/10.1007/s11094-013-0931-4},
number = {4},
pages = {217--218},
doi = {10.1007/s11094-013-0931-4}
}
MLA
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MLA Copy
Sokolenko, V. A., et al. “Improved Synthesis of 2-(1-Adamantyl)-4-bromophenol and 2-(1-Adamantyl)-4-bromoanisole, Intermediates in Adapalene Synthesis.” Pharmaceutical Chemistry Journal, vol. 47, no. 4, Jul. 2013, pp. 217-218. https://doi.org/10.1007/s11094-013-0931-4.