Potential Synthetic Adaptogens. II. Synthesis and Pharmacological Activity of New Conformationally Labile Bromantane Analogs, N-[(Adamantan-1-YL)Methyl]-4-Bromoanilines
A S Babushkin
1
,
M B Navrotskii
1
,
I A Novakov
1
,
B S Orlinson
1
,
M D Robinovich
1
,
D S Sheikin
1
,
S N Voloboev
2
2
Lukoil Volgograd Oil Refinery, Volgograd, Russia
|
Publication type: Journal Article
Publication date: 2017-03-13
scimago Q4
wos Q4
SJR: 0.219
CiteScore: 1.4
Impact factor: 1.0
ISSN: 0091150X, 15739031
Drug Discovery
Pharmacology
Abstract
New structural analogs of bromantane with greater conformational lability than the prototype were synthesized. Their physiological activity profiles were assessed in vivo. It was found that the analogs could be prepared under much milder conditions than bromantane and that their biological activity profiles dependedstrongly on the nature of adamantane substitution.
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Babushkin A. S. et al. Potential Synthetic Adaptogens. II. Synthesis and Pharmacological Activity of New Conformationally Labile Bromantane Analogs, N-[(Adamantan-1-YL)Methyl]-4-Bromoanilines // Pharmaceutical Chemistry Journal. 2017. Vol. 50. No. 12. pp. 781-787.
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Babushkin A. S., Navrotskii M. B., Novakov I. A., Orlinson B. S., Robinovich M. D., Sheikin D. S., Voloboev S. N. Potential Synthetic Adaptogens. II. Synthesis and Pharmacological Activity of New Conformationally Labile Bromantane Analogs, N-[(Adamantan-1-YL)Methyl]-4-Bromoanilines // Pharmaceutical Chemistry Journal. 2017. Vol. 50. No. 12. pp. 781-787.
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TY - JOUR
DO - 10.1007/s11094-017-1531-5
UR - https://doi.org/10.1007/s11094-017-1531-5
TI - Potential Synthetic Adaptogens. II. Synthesis and Pharmacological Activity of New Conformationally Labile Bromantane Analogs, N-[(Adamantan-1-YL)Methyl]-4-Bromoanilines
T2 - Pharmaceutical Chemistry Journal
AU - Babushkin, A S
AU - Navrotskii, M B
AU - Novakov, I A
AU - Orlinson, B S
AU - Robinovich, M D
AU - Sheikin, D S
AU - Voloboev, S N
PY - 2017
DA - 2017/03/13
PB - Springer Nature
SP - 781-787
IS - 12
VL - 50
SN - 0091-150X
SN - 1573-9031
ER -
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@article{2017_Babushkin,
author = {A S Babushkin and M B Navrotskii and I A Novakov and B S Orlinson and M D Robinovich and D S Sheikin and S N Voloboev},
title = {Potential Synthetic Adaptogens. II. Synthesis and Pharmacological Activity of New Conformationally Labile Bromantane Analogs, N-[(Adamantan-1-YL)Methyl]-4-Bromoanilines},
journal = {Pharmaceutical Chemistry Journal},
year = {2017},
volume = {50},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s11094-017-1531-5},
number = {12},
pages = {781--787},
doi = {10.1007/s11094-017-1531-5}
}
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MLA
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Babushkin, A. S., et al. “Potential Synthetic Adaptogens. II. Synthesis and Pharmacological Activity of New Conformationally Labile Bromantane Analogs, N-[(Adamantan-1-YL)Methyl]-4-Bromoanilines.” Pharmaceutical Chemistry Journal, vol. 50, no. 12, Mar. 2017, pp. 781-787. https://doi.org/10.1007/s11094-017-1531-5.